Drugs affecting the nervous system

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Last updated: March 20, 2017

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First submitted	March 20, 2017
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Average score	16.7%
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Hint	Answer
Analgesic, binds CNS opiate receptors to decrease pain.	Morphine
Blocks effects of opioids, especially in overdose	Naloxone
Nicotinic cholinergic receptor agonist	Nicotine
Antiemitic - highly specific 5-HT3R antagonist	Ondansetron
MAO inhibitor used as antidepressant, anxiolytic	Phenelzine
Anti-seizure medication, voltage dependent block of VGNa channels, begins with Ph..	Phenytoin
Inverse alpha1 agonist used as anxiolytic	Prazosin
Used in anaesthesia to decrease consciousness, potentiates GABAA receptor activity.	Propofol
Induces, maintains general anaesthesia. Positive modulator of GABAA receptor	Sevoflurane
Opioid pain medication, begins with T...	Tramadol
Tricyclic antidepressant - 5HT/NA reuptake inhibitor	Amitriptyline
Used to treat epilepsy, bipolar disorder. Increased levels of GABA, blocked of VGNa channels	Valproate
Non-depolarising block at NMJ	Vecuronium
Antidepressant - 5-HT/ NA reuptake inhibitor, begins with V...	Venlafaxine
5-HT receptor agonist used in treatment of migraine	Sumatriptan

Hint	Answer
Insomnia treatment, increases effect of GABA at GABAA receptor	Temazepam
Used for peripheral nerve block/ epidural block - binds intracellular portion of VGNa channels, preventing depolarisation.	Bupivacaine
Anxiolytic psychotropic, 5-HT1A partial agonist.	Buspirone
Use-dependent VGNa channel blocker, used in treatment of epilepsy and neuropathic pain.	Carbamazepine
Antipsychotic, primarily blocking D2 receptors	Chlorpromazine
Atypical antipsychotic, partial 5-HT1A agonist as well as D2 antagonist	Clozapine
Converted by Cyp450 to morphine, used in pain relief	Codeine
Prevents accommodation of eye, muscarinic antagonist	Cyclopentolate
Positive modulator of GABAA receptors, used in treatment of anxiety, insomnia	Diazepam
SSRI antidepressant, begins with F...	Fluoxetine
Antipsychotic with high affinity D2 antagonism, begins with H...	Haloperidol
General anaesthetic, binds GABA, glutamate, glycine receptors - exact mechanism not clearly delineated.	Isoflurane
Dopamine precursor, can cross blood-brain-barrier. Used in Parkinson's treatment.	L-DOPA
Local anaesthetic, blocks Na channels	Lidocaine
Treatment of major depressive disorder, begins with L...	Lithium

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