Atherosclerosis

What is the main cause of thrombosis in veins? (due to slow blood flow)

What is the eponymous name for the laminations that occur in thrombi in arteries?

What is the process in which new blood vessels form through the thrombus called?

What is the medical term for too few platelets?

What is the most internal layer of a large artery?

What is the most external layer of an artery?

What is described? A disease of the intima of large and medium sized arteries.

What disease may be caused by the above but instead is purely a loss of elasticity and physical hardening of the arterial wall, from any cause?

What is considered as good cholesterol as it moves cholesterol from peripheral tissues to the liver for excretion through bile?

What pathway leads to production of foam cells due to macrophages aiming to take up modified lipoproteins?

What is the banner term for an abnormal concentration of lipoproteins in the blood. this can include hypercholestrolaemia or a secondary disease leading to it (diabetes).

By what process to macrophages take up oxidised lipoproteins to become foam cells?

Macrophages activate smooth muscle using molecules (PDGF and FGF) this leads to it turning from a contractile to what type of phenotype?

What are the precussors to atherosclerosis that can be seen on the intima of arteries of teenagers?

In the intima of fibro-fatty atherosclerotic plaques there are three key regions, these are. Fibrous cap, lipid core and what third (containing foam cells and where angiogenesis may take place)?

What is described? A localised enlargement of an artery?

What is gradual narrowing of the lumen due to atherosclerosis referred to as?