Hint | Answer | % Correct |
---|---|---|
What is being described here? A mass composed from blood constituents within the circulation during life. | Thrombus | 100%
|
What is it called when this mass travels off and blocks a vessel elsewhere? | Embolism | 75%
|
What is described? "Anuclear discs, with a life span of ~7 days, produced by fragmentation of the cytoplasm of megakaryocytes in bone marrow" | Platelet | 75%
|
What system is used to disassemble the plug afterwards? | Fibrinolytic | 50%
|
What gaseous substance that can cause vasodilatation is a potent platelet inhibitor? | Nitric oxide/NO | 50%
|
What is the name for the key active protease in this system? | Plasmin | 50%
|
What is the initial block that occurs due to fibrinogen binding the platelets together referred to as? | Primary haemostatic plug | 50%
|
What condition whos name derives from the purple colour of the regions of skin affected occurs due to reduced platelet count and bleeding from skin capillaries? | Purpura | 50%
|
Activation of the coagulation system leads to the production of which enzyme that then causes conversion of fibrinogen into insoluble fibrin, and creates a solid mass through fusion? | Thrombin | 50%
|
What chemical that is released leads to aggregation of them due to increasing their recruitment? | Thromboxane A2/TxA2 | 50%
|
What factor mediates adhesion of them, by bridging between exposed collagen (in endothelial damage) and glycoprotein IB on their surface? | Von Willebrand | 50%
|
Two of the three are, changes in vessel wall, changes in blood constituents, and what third aspect of blood change may predispose? | Flow | 25%
|
After adhesion activation of them occurs comprising of two key components secretion of chemicsal signals and which other? | Shape change | 25%
|
What molecule that is produced by endothelial cells leads to activation of fibrinolysis? | Tissue Plasminogen Activator/tPA | 25%
|
Whose set of three rules defines the predisposing factors for thrombus formation? | Virchow's | 25%
|
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