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1.
Where is the heart within the Thorax?
2.
What is the outer layer of heart tissue called, which protects the heart?
3.
What is the approximate length and mass of a human heart?
4.
What is the average heart stroke volume?
5.
What 2 values do you multiply to work out the Cardiac output?
Stroke volume and heart mass
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Heart rate and heart mass
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Heart rate and stroke volume
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Stroke volume and residual capacity
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6.
What does the cardiac reserve represent?
Number of heart beats per minute
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The difference between resting and maximum cardiac output
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The amount of blood that can be in the heart at one time
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The amount of blood pumped by the heart during each beat
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7.
Which side of the heart has a thicker muscle wall?
There is no muscle around the ventricles, only the atria
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8.
What is the name of the heart muscle?
9.
What is the name of the tissue which lines heart chambers?
10.
Which valve is between the Right Atria and Right Ventricle?
11.
Which valve is between the Right Ventricle and Pulmonary Trunk?
12.
Which valve is between the Left Atria and Left Ventricle?
14.
Which muscles are the heart valves connected to, and in what phase do they contract?
15.
What is the sound S1?
Blood rushing through the ventricles during ventricular systole
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Closing of semilunar valves at the end of ventricular systole
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Closing of AV valves at the start of ventricular systole
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Muscles in the heart contracting during ventricular systole
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16.
What is the sound S2?
Blood rushing through the ventricles during ventricular systole
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Closing of semilunar valves at the end of ventricular systole
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Closing of AV valves at the start of ventricular systole
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Muscles in the heart contracting during ventricular diastole
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17.
The release of what ion triggers contraction of cardiac muscle?
18.
What do actin and myosin do in cardiac muscle?
React with potassium to fuel heart contraction
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Contribute to ATP hydrolysis
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19.
What triggers release in the sliding filament mechanism?
20.
What causes conformational change in the sliding filament mechanism?
21.
What causes rebinding in the sliding filament mechanism?
22.
What causes power stroke in the sliding filament mechanism?
23.
What proteins prevent the interaction of actin and myosin?
Myoglobin and Myoglomyosin
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Troponin and Tropomyosin
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24.
Which ion binds to the above proteins causing conformational change and the interaction of actin and myosin?
25.
Which of the 7 heart phases are systole?
26.
What triggers calcium release from the sarcoplasmic reticulum after trigger calcium is received from another source?
27.
What is the source of the trigger calcium?
Extracellular space through L type channels
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From Actin and Myosin through the intracellular matrix
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28.
What does the calcium interact with, what does it cause, and what does it uncover?
TN-C, TN-I, Myosin binding site on actin
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TN-I, TN-C, Actin binding site on Myosin
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TN-A, TN-B, Myosin Binding site on Actin
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TN-B, TN-A, Actin Binding site on Myosin
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29.
What happens to the calcium in the cell after this?
It is reabsorbed into the SR and then removed from the cell
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It binds to the uncovered binding site
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It is transported directly into other cells
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It goes into the mitochondria
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30.
What happens as the concentration of calcium decreases?
It causes an increase in ATP hydrolysis
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It causes phosphates to start binding to key sites
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It dissociates with the site it originally bound to
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It causes the cell to lyse
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31.
Which method asides from the Ca pump is calcium removed from cells?
32.
What regulates electrical activity in the heart?
33.
What is the Nernst potential?
Voltage required to promote activity in the whole heart
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Voltage required to stop flow of ions to due concentration gradient
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Highest potential voltage a heart can take without damage
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Lowest potential voltage a heart can use to function normally
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34.
Which 3 pumps are used to regulate concentration of ions?
35.
What does inotropy mean?
velocity of signal conduction by cardiomyocytes
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strength of contraction
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36.
What does chronotropy mean?
strength of contraction
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velocity of signal conduction by cardiomyocytes
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37.
What does tachycardia mean?
velocity of signal conduction by cardiomyocytes
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strength of contraction
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38.
What does bradycardia mean?
velocity of signal conduction by cardiomyocytes
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39.
What does lusitropy mean?
velocity of signal conduction by cardiomyocytes
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myocardial excitability
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40.
What does bathmotropy mean?
strength of contraction
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myocardial excitability
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velocity of signal conduction by cardiomyocytes
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41.
What is the Frank Starling mechanism?
The more the ventricle is filled with blood during diastole, the lesser the stroke volume
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The less the ventricle is filled with blood during diastole, the greater the stroke volume
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The more the ventricle is filled with blood during diastole, the greater the stroke volume
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The less the ventricle is filled with blood during diastole, the greater the cardiac output
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42.
What is the preload?
Stretch of cardiac muscle during diastole
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Amount of blood that can fit into the right ventricle
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Stretch of heart muscle during systole
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Amount of blood that can fit into the left ventricle
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43.
What is afterload
Stretch of heart muscle during systole
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The amount of blood the heart pumps per beat
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Stretch of cardiac muscle during diastole
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Tension produced by the heart to eject blood
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44.
What is a baroreceptor?
Nerve endings in the adventitia of the sarcarotid sinus and aortic arch
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Nerve endings in the myocardium
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Nerve endings in the epivenentitia of the carotid sinus and aortic arch
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Nerve endings in the adventitia of the carotid sinus and aortic arch
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