Synthetic Routes - OCR A Level Chemistry

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Last updated: June 17, 2023
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First submittedJune 17, 2023
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1. What reagents do you use to go from Alkene to Alkane?
Ethanolic NH3
H2 / Ni
NaHCO3
Acidified potassium dichromate / reflux
2. What reagents do you use to go from Alkene to Alcohol?
H2O(g) / H3PO4
HCN
H2 / Ni
Smirnoff's reagent
3. What reagents for Alkane to Haloalkane?
Uranium
NaX / H2SO4 / heat
KCN / Uranium
Radical substitution: X2 / UV light
4. Haloalkane to Alcohol?
NaOH / heat
NaBH4
KCN / Ununoctium
HCl / heat
5. Alcohol to Alkene?
NaBH4
X2 / UV Light
H2SO4 / heat
Ethanolic KCN
6. You reflux tertiary alcohol + acidified potassium dichromate What do you get?
Aldehyde
No change
Carboxylic acid
Ketone
7. Butan-1-ol is distilled with acidified potassium dichromate. What do you get?
Butanoic Acid
Butanone
Butanal
But-2-ene
8. Butan-2-one is reacted with Z to form an Butan-2-ol. What is Z?
HCN
H2SO4 / reflux
Cinnamaldehyde
NaBH4
9. Walter is doing a PAG, and needs to make methanoyl chloride from methanol. What reagents does he use?
Add SOCl2
Reflux with acidified potassium dichromate
NaBH4
1. Reflux with acidified potassium dichromate THEN 2. Add SOCl2
10. What can Walter NOT make, in one step, using an Acyl Chloride?
Secondary amide, by adding a primary amine
Carboxylate salt, by adding NaOH
Primary amide, by adding ammonia
Ester, by adding alcohol
11. How can you reduce a nitrile to an amine?
ethanolic KCN
ethanolic NH3
UV and X2
H2 / Ni
12. Walter wants to make a secondary amine from a primary amine. What reagents does he use?
CH3Cl + NH3 / Ethanol
CH3Cl + KCN / Ethanol
CH3Cl + CH2(Cl)CH2CH(CH3)NH2 / Ethanol
HNO3 / H2SO4
13. In the last step of Walter's synthesis, he is alkylating benzene. What reagent and catalyst does he use, and what is the name of this process?
RNH2 / AlCl3 / Friedel-Crafts Alkylation
RCl / AlCl3 / Schade-Havertz Acylation
RCl / AlBr3 / Friedel-Crafts Alkylation
RCl / AlCl3 / Friedel-Crafts Alkylation
14. NO2 to NH2?
Sn + HCl then add NaS2O3
Sn + HCl then add NaOH, to deprotonate NH3+
Sb + HCl then add NaS2O3
Sb + HCl then add NaOH, to deprotonate NH3+
15. I am nitrating phenol What reagents do I need and what position will the substitution occur?
HNO3 / H2SO4, 3
HNO3 only, 2 and 4
HNO3 only, 3
HNO3 / H2SO4, 2 and 4
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