Pathology

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Quiz by MedSoc
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Last updated: December 10, 2018
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First submittedDecember 10, 2018
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Average score21.4%
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Hint
Answer
What is the name given to the study of causes of disease? (.....ology)
Aetiology
What tops the WHOs top 10 causes of death globally?
Ischaemic heart disease
What is second?
Stroke
Who proposed that cell injury is the basis of disease?
Virchow
What is the name for a loss of both cell volume and number of cells?
Atrophy
What is the name given to an adaptation when under stress that may not revert back to normal when stress is removed?
Dysplasia
When under stress cells may adapt by reducing complexity, part of this process may involve digestion of their own organelles, what is the banner term that refers to this?
Autophagy
Hint
Answer
Which of apoptosis and necrosis activates the immune system when it occurs?
Necrosis
What is the name for the main group of enzymes that are involved in the process of apoptosis?
Caspase
What type of molecules are both ones which are used by macrophages to kill off pathogens, and incredibly dangerous to host cells as may cause scission in nucleic acids?
Reactive oxygen species
When tissue is re-oxygenated after hypoxia these molecules may be produced leading to what injury, that involves destruction of the endothelial lining of small blood vessels?
Reperfusion
When under cellular stress HSFs are triggered to dissociate translocating to the nucleus and down regulating protein production, it also upregulates the production of which molecule, that is then used to correctly fold denatured proteins?
Heat shock protein
What is the name of the pathway that leads to reduced protein transcription etc. that utilises the transcription factor AP1?
Stress Kinase
What is the name of the response that ensures that a cells rate of protein production does not exceed the speed at which it can fold the proteins? As this would lead to aggregation of the proteins.
Unfolded protein response
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