Clue
|
Drug
|
CNS stimulant, indirectly acting sympathomimetic (IAS)
|
amphetamines
|
peptide hormone produced by beta cells in pancreas
|
insulin
|
Loop diuretic, inhibits NKCC2 in thick ascending limb of loop of Henle
|
furosemide
|
non-selective beta agonist
|
isoprenaline
|
blocks voltage-gated sodium channels, used as local anaesthetic or class I antidysrhythmic
|
lidocaine
|
predominantly beta-1 adrenergic agonist
|
dobutamine
|
prevents vesicular release of ACh, causing paralysis of muscles
|
botulinum toxin
|
competitive inverse agonist of muscarinic cholinergic receptors, non-selective
|
atropine
|
thiazide diuretic, inhibits sodium reabsorption at beginning of DCT
|
bendroflumethiazide
|
endogenous catecholamine, favours beta adrenergic receptors
|
adrenaline
|
potassium-sparing diuretic, blocks eNaC in DCT
|
amiloride
|
class III antidysrhythmic agent, prolongs phase 3 of cardiac action potential
|
amiodarone
|
clinically used cardiac glycoside, inhibits sodium/potassium ATPase in myocardium
|
digoxin
|
selective beta-1 adrenergic antagonist
|
atenolol
|
osmotic diuretic
|
mannitol
|
reversible AChE inhibitor, used to improve muscle tone in myasthenia gravis
|
neostigmine
|
proton-pump inhibitor
|
omeprazole
|
cardiac glycoside not clinically used, historically used in poison arrows
|
ouabain
|
antibiotic, discovered by Fleming
|
penicillin
|
short-acting beta-2 agonist
|
salbutamol
|
non-depolarising blocking agent, competes for cholinergic receptors at motor end plates.
|
vecuronium
|
diuretic - carbonic anhydrase inhibitor
|
Acetazolamide
|
NSAID, COX inhibitor
|
aspirin
|
depolarising neuromuscular blocker, acting on nicotinic receptors
|
suxamethonium
|
L-type calcium channel blocker
|
verapamil
|
nicotinic cholinergic receptor antagonist
|
tubocurarine
|
H2 histamine receptor antagonist
|
ranitidine
|
potassium-sparing diuretic, aldosterone antagonist
|
spironolactone
|
binds to voltage-gated sodium channels, blocking passage of sodium ions, found in pufferfish
|
tetrodotoxin
|
non-selective beta adrenergic receptor blocker
|
propranolol
|
Class Ib antidysrhythmic, used in treatment of some forms of long QT syndrome
|
mexiletine
|