Statistics for diabetes drugs

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General Stats

  • This quiz has been taken 13 times
  • The average score is 6 of 21

Answer Stats

HintAnswer% Correct
what are examples of each?insulin
100%
what are the treatment options for diabetes?insulin and insulin analogues
100%
what is Type 1 diabetes?insulin-dependent (absolute deficiency of insulin caused by an autoimmune condition)
45%
insulin secretagogues (sulfonylureas & meglitinides)
36%
what is the biochemical function of insulin?to trigger the absorption of glucose from the blood into the liver, skeletal muscle and fat tissue
36%
what are their mechanisms of action?triggers the absorption of glucose from the blood into the liver, skeletal muscle and fat tissue
36%
improve the response of target cells to insulin by either:
- decreasing hepatic gluconeogenesis & reducing intestinal absorption of sugars (biguanides)
or:
- activation of peroxisome proliferator-activated receptors (thiazolidinediones)
27%
insulin sensitisers (biguanides & thiazolidinediones)
27%
what is Type 2 diabetes?non-insulin-dependent (decreased ability of tissues to respond to normal levels of insulin)
27%
promote insulin release from the b-cells of the pancreas by:
- binding to and close ATP-sensitive K+ channels on b-cells
- depolarising the cells and opens Ca2+ channels
- triggering fusion of insulin granules with cell membrane
27%
what is the biochemical function of glucagon?to trigger the release of glucose into the blood from the liver via gluconeogenesis and glycogenolysis
27%
dyslipidaemia
18%
what are the biochemical features of Type 2 diabetes?hyperglycaemia
18%
what are the biochemical features of Type 1 diabetes?hyperglycaemia and ketoacidosis
18%
hypertriacylglycerolaemia
18%
oral hypoglycemic drugs
18%
acarbose, miglitol, voglibose
9%
a-glucosidase inhibitors
9%
gastrointestinal hormones
9%
competitively inhibit the action of the enzyme a-glucosidase, that breaks carbohydrates into monosaccharides
0%
glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic peptide (GIP), peptide YY (PYY)
0%

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