Unlock Method | Achievement | % Correct |
---|---|---|
Defeat Mom's Heart 10 times | ??? | 100%
|
Defeat Mother as Eden | M | 89%
|
Hold 55 coins at one time | Cain | 74%
|
Take 3 Devil Deals in one run | Azazel | 63%
|
Have 7 or more red heart containers at one time | Magdalene | 63%
|
Defeat Satan | Judas | 58%
|
Beat Chapter 4 | Eden | 53%
|
Don't pick up any hearts for 2 floors in a row | Eve | 53%
|
Have 4 or more soul hearts at one time | Lazarus | 53%
|
Die in a Sacrifice Room while holding Missing Poster | The Lost | 53%
|
Defeat Mega Satan as ??? | Blue Baby | 47%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Isaac | The Broken | 47%
|
Become Guppy | Guppy's Hairball | 42%
|
Complete Pica Run (Challenge #41) | Ice Cube | 42%
|
Defeat Mom's Heart 11 times | It Lives! | 42%
|
Defeat Mother | Jacob and Esau | 42%
|
Defeat Steven | Little Steven | 42%
|
Defeat Mega Satan as every character (Except Tainted characters) | Mega | 42%
|
Beat 2 floors in a row without taking damage | Samson | 42%
|
Defeat Isaac as ??? | The D6 | 42%
|
It's complicated | The Forgotten | 42%
|
Defeat Isaac 5 times | The Polaroid | 42%
|
Defeat Mom | A Cube of Meat | 37%
|
Beat Chapter 1 without taking damage | Basement Boy | 37%
|
Defeat Ultra Greedier as Tainted Forgotten | Death? | 37%
|
Complete The Family Man (Challenge #19) | Epic Fetus | 37%
|
Defeat ??? and The Lamb | Golden God | 37%
|
Donate 1000 coins to the Greed Donation Machine | Keeper | 37%
|
Defeat Ultra Greed as Azazel | Lilith | 37%
|
Defeat Gish | Little Gish | 37%
|
Beat Chapter 4 without taking damage | Mama's Boy | 37%
|
Defeat Satan 5 times | The Negative | 37%
|
Pick up every item in the game, unlock all secrets and endings, complete the Bestiary (Afterbirth+) | 1000000% | 32%
|
Defeat Mega Satan | Apollyon | 32%
|
Defeat Mom's Heart or It Lives! on Hard mode as Lazarus without losing a life | Bethany | 32%
|
Beat Chapter 3 without taking damage | Dark Boy | 32%
|
Unlock every other achievement and pick up every item in the game (Repentance) | Dead God | 32%
|
Defeat C.H.A.D. | Little C.H.A.D. | 32%
|
Use 5 Gulp! pills in a single run (Can use Placebo) | Marbles | 32%
|
Pick up all non-DLC items and collect all non-DLC secrets and endings (Except The Lost and his 6 unlockable items) | !Platinum God! | 32%
|
Complete 3 Victory Laps and start a 4th | RERUN | 32%
|
Defeat Mom's Heart 2 times | Rubber Cement | 32%
|
Complete Pitch Black (Challenge #1) | Rune of Hagalaz | 32%
|
Beat Chapter 2 without taking damage | Spelunker Boy | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as The Lost | The Baleful | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Eve | The Curdled | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Magdalene | The Dauntless | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Jacob and Esau | The Deserter | 32%
|
Defeat Ultra Greedier as Tainted Azazel | The Devil? | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Apollyon | The Empty | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as The Forgotten | The Fettered | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Lilith | The Harlot | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Cain | The Hoarder | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Keeper | The Miser | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Samson | The Savage | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as ??? | The Soiled | 32%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Bethany | The Zealot | 32%
|
Pick up Ball of Bandages 4 times in a single run | A Bandage | 26%
|
Defeat all bosses in Mines | Ashpit | 26%
|
Destroy 100 tinted rocks | A Small Rock | 26%
|
Defeat Mother | A Strange Door | 26%
|
Defeat Delirium as Tainted Cain | Bag of Crafting | 26%
|
Defeat Delirium as Tainted Samson | Berserk! | 26%
|
It's complicated | Bone Heart | 26%
|
Earn all Hard mode Completion Marks for all characters | Death Certificate | 26%
|
Complete Waka Waka (Challenge #17) | Death's Touch | 26%
|
Defeat Delirium as Isaac | D Infinity | 26%
|
Defeat all bosses in Downpour | Dross | 26%
|
Defeat Mom's Heart 5 times | Everything Is Terrible!!! | 26%
|
Donate 111 coins to the Greed Donation machine | Everything Is Terrible 2!!! | 26%
|
Defeat Delirium as Tainted Lazarus | Flip | 26%
|
Defeat The Beast as Tainted Isaac | Glitched Crown | 26%
|
Defeat Mother as Cain | Guppy's Eye | 26%
|
Defeat Hush as Lilith | Incubus | 26%
|
Defeat Mom's Heart 6 times | Ipecac | 26%
|
Defeat Delirium for the 1st time | Lil Delirium | 26%
|
Defeat Ultra Greed as Samson | Lusty Blood | 26%
|
Defeat Mega Satan as Tainted Isaac | Mega Chest | 26%
|
Defeat Satan as Isaac | Mom's Knife | 26%
|
Defeat Mom's Heart 11 times and unlock Marbles | Pica Run | 26%
|
Complete Boss Rush as Jacob and Esau | Rock Bottom | 26%
|
Complete High Brow (Challenge #2) | Rune of Jera | 26%
|
Complete Solar System (Challenge #6) | Rune of Perthro | 26%
|
Defeat The Beast as Tainted Lost | Sacred Orb | 26%
|
Defeat It Lives! 30 times | Scarred Womb | 26%
|
Complete Boss Rush and defeat Hush as Tainted ??? | Soul of ??? | 26%
|
Complete Boss Rush and defeat Hush as Tainted Azazel | Soul of Azazel | 26%
|
Complete Boss Rush and defeat Hush as Tainted Bethany | Soul of Bethany | 26%
|
Complete Boss Rush and defeat Hush as Tainted Eden | Soul of Eden | 26%
|
Complete Boss Rush and defeat Hush as Tainted Eve | Soul of Eve | 26%
|
Complete Boss Rush and defeat Hush as Tainted Isaac | Soul of Isaac | 26%
|
Complete Boss Rush and defeat Hush as Tainted Jacob | Soul of Jacob and Esau | 26%
|
Complete Boss Rush and defeat Hush as Tainted Judas | Soul of Judas | 26%
|
Complete Boss Rush and defeat Hush as Tainted Lazarus | Soul of Lazarus | 26%
|
Complete Boss Rush and defeat Hush as Tainted Lilith | Soul of Lilith | 26%
|
Complete Boss Rush and defeat Hush as Tainted Magdalene | Soul of Magdalene | 26%
|
Complete Boss Rush and defeat Hush as Tainted Samson | Soul of Samson | 26%
|
Complete Boss Rush and defeat Hush as Tainted Forgotten | Soul of The Forgotten | 26%
|
Complete Boss Rush and defeat Hush as Tainted Keeper | Soul of the Keeper | 26%
|
Complete Boss Rush and defeat Hush as Tainted Lost | Soul of The Lost | 26%
|
Defeat Mom | Speed | 26%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Azazel | The Beknighted | 26%
|
Defeat a Harbinger | The Book of Revelations | 26%
|
Defeat all 7 Deadly SIns | The Book of Sin | 26%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Eden | The Capricious | 26%
|
Complete Boss Rush as The Lost | The D100 | 26%
|
Defeat ??? as Isaac | The D20 | 26%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Judas | The Deceiver | 26%
|
Defeat Ultra Greedier as Tainted ??? | The Emperor? | 26%
|
Defeat Ultra Greedier as Tainted Eve | The Empress? | 26%
|
Use the Red Key or Cracked Key to unlock the secret closet in Home as Lazarus | The Enigma | 26%
|
Defeat Ultra Greedier as Tainted Lost | The Fool? | 26%
|
Defeat Mom | The Harbingers | 26%
|
Defeat Ultra Greedier as Tainted Jacob | The Moon? | 26%
|
Defeat The Lamb as The Lost | The Soul | 26%
|
Defeat Ultra Greedier as Tainted Jacob | The Sun? | 26%
|
Defeat Mom | The Womb | 26%
|
Defeat The Beast as Tainted Eden | TMTRAINER | 26%
|
Defeat Delirium as Apollyon | Void | 26%
|
Defeat Delirium as Tainted Apollyon | Abyss | 21%
|
Defeat Satan as Bethany, defeat Mom's Heart 11 times, and unlock Maggy's Faith | Baptism by Fire | 21%
|
Defeat ??? as Jacob and Esau | Birthright | 21%
|
Defeat Ultra Greedier as Apollyon | Black Rune | 21%
|
Use the Blood Donation Machine 30 times | Blood Bag | 21%
|
Defeat Mother as Samson | Bloody Gust | 21%
|
Defeat Isaac as Samson | Bloody Lust | 21%
|
Unlock Bethany, Blood Bag, and It Lives! | Bloody Mary | 21%
|
Destroy 10 tinted rocks and defeat Mom's Heart 11 times | Blue Bomber | 21%
|
Defeat Ultra Greed as Lilith | Box of Friends | 21%
|
Defeat Isaac 5 times | BRAINS! | 21%
|
Defeat The Beast as Lilith | C Section | 21%
|
Have 7 or more red heart containers at one time | Cursed! | 21%
|
Defeat Ultra Greedier as Isaac | D1 | 21%
|
Defeat Delirium as Tainted Judas | Dark Arts | 21%
|
Beat Chapter 6 without taking damage | Dead Boy | 21%
|
Participate in 31 Daily Challenges (They don't have to be consecutive) | Dedication | 21%
|
Unlock Tainted Eden | DELETE THIS | 21%
|
Defeat Delirium | Delirious | 21%
|
Defeat The Lamb as Azazel | Demon Baby | 21%
|
Defeat Mother as Tainted Isaac | Dice Bag | 21%
|
Defeat The Beast as Tainted Apollyon | Echo Chamber | 21%
|
Defeat It Lives! 16 times | Flooded Caves | 21%
|
Defeat all bosses in Mausoleum | Gehenna | 21%
|
Defeat Delirium as Tainted Lilith | Gello | 21%
|
Defeat Mega Satan as Tainted Azazel | Hell Game | 21%
|
Defeat Delirium as Tainted Azazel | Hemoptysis | 21%
|
Unlock Tainted Forgotten | Hot Potato | 21%
|
Defeat Delirium as Tainted ??? | IBS | 21%
|
Defeat Delirium as Tainted Keeper | Keeper's Kin | 21%
|
Complete Backasswards (Challenge #31) | Laz Bleeds More! | 21%
|
Donate 879 coins to the Greed Donation Machine | Lost holds Holy Mantle | 21%
|
Defeat The Lamb as Magdalene | Maggy's Faith | 21%
|
Earn all Hard mode Completion Marks for all non-Tainted characters) | Mega Mush | 21%
|
Complete Boss Rush as Lazarus | Missing No. | 21%
|
Beat Chapter 1 | Monstro's Tooth | 21%
|
Open 20 locked chests | Mr. ME! | 21%
|
Destroy 10 tinted rocks | Mr. Mega | 21%
|
Defeat Mega Satan as Tainted Magdalene | Queen of Hearts | 21%
|
Donate 500 coins to the Donation Machine | Red Candle | 21%
|
Open Mom's Chest in Home | Red Key | 21%
|
Unlock Tainted Jacob | Red Redemption | 21%
|
Defeat Mother as Bethany | Revelation | 21%
|
Complete Cat Got Your Tongue (Challenge #8) | Rune of Algiz | 21%
|
Complete Purist (Challenge #20) | Rune of Berkano | 21%
|
Complete Darkness Falls (Challenge #4) | Rune of Dagaz | 21%
|
Complete Head Trauma (Challenge #3) | Rune of Ehwaz | 21%
|
Complete Boss Rush and defeat Hush as Tainted Apollyon | Soul of Apollyon | 21%
|
Complete Boss Rush and defeat Hush as Tainted Cain | Soul of Cain | 21%
|
Defeat Delirium as Tainted Isaac | Spindown Dice | 21%
|
Complete Isaac's Awakening (Challenge #39) | Spirit Sword | 21%
|
Donate 999 coins to the Donation Machine | Stop Watch | 21%
|
Complete Suicide King (Challenge #7) | Defeat Mom's Heart 11 times and unlock Lazarus | Suicide King | 21%
|
Defeat Delirium as Tainted Eve | Sumptorium | 21%
|
Pick up Cube of Meat 4 times in a single run | Super Meat Boy | 21%
|
Complete The Host (Challenge #18) | Tech.5 | 21%
|
Beat all Caves bosses (Except Bumbino) | The Catacombs | 21%
|
Beat all Basement bosses (Except Baby Plum) | The Cellar | 21%
|
Complete Hot Potato (Challenge #42) | The Chariot? | 21%
|
Destroy 30 Slot Machines | The D4 | 21%
|
Defeat Mom | The Guardian | 21%
|
Complete Red Redemption (Challenge #44) | The Hermit? | 21%
|
Beat all Depths bosses (Except Reap Creep) | The Necropolis | 21%
|
Pick up 3 items with the "stars" item tag in a single run | The Planetarium | 21%
|
Pick up all non-DLC items and collect all non-DLC secrets and endings | The Real Platinum God | 21%
|
Die 100 times | The Scissors | 21%
|
Defeat Ultra Greedier as Tainted Isaac | The Stars? | 21%
|
Defeat Ultra Greedier as Tainted Apollyon | The Tower? | 21%
|
Defeat Ultra Greedier as Tainted Eden | The World? | 21%
|
Defeat The Beast as Tainted Lilith | Twisted Pair | 21%
|
Defeat Mega Satan as Tainted Eden | Wild Card | 21%
|
Defeat Mom | XXXXXXXXL | 21%
|
Get a 3-win streak using different characters each time | 5 Nights at Mom's | 16%
|
Defeat Mom, Mom's Heart, or It Lives! using The Bible | A Halo | 16%
|
Defeat Delirium as Tainted Jacob | Anima Sola | 16%
|
Defeat Mom | Aprils Fool | 16%
|
Defeat Mom's Heart 8 times | A Quarter | 16%
|
Defeat Hush 3 times | A Secret Exit | 16%
|
Defeat The Beast as Tainted Azazel | Azazel's Rage | 16%
|
Use I - The Magician or Telepathy for Dummies while already having homing tears | Baby-Bender | 16%
|
Donate 150 coins to the Donation Machine | Black Candle | 16%
|
Defeat Isaac as Eden | Blank Card | 16%
|
Sleep in 10 beds | Blanket | 16%
|
Complete The Guardian (Challenge #30) | Blank Rune | 16%
|
Donate 900 coins to the Donation Machine | Blue Candle | 16%
|
Defeat Mom's Heart 10 times | Blue Womb | 16%
|
Earn all Hard mode Completion Marks as The Forgotten | Bone Baby | 16%
|
Defeat Isaac as Bethany | Book of Virtues | 16%
|
After destroying Hornfel's minecart, kill him before he escapes | Brimstone Bombs | 16%
|
Complete Seeing Double (Challenge #40) | Broken Glasses | 16%
|
Complete 7 Daily Challenges | Broken Modem | 16%
|
Defeat Mom's Heart 11 times | Burning Basement | 16%
|
Unlock Tainted Cain | Cantripped! | 16%
|
Complete When Life Gives You Lemons (Challenge #12) | Card Against Humanity | 16%
|
Become Guppy | Cat Got Your Tongue | 16%
|
Defeat Mega Satan as Tainted Bethany | Confessional | 16%
|
Defeat Delirium as Keeper | Crooked Penny | 16%
|
Defeat Mother as Tainted Lost | Crystal Key | 16%
|
Defeat Hush as Cain | D12 | 16%
|
Complete PRIDE DAY! (Challenge #28) | D8 | 16%
|
Pick up both key pieces from the Angels in one run | Dad's Key | 16%
|
Defeat The Lamb as Jacob and Esau | Damocles | 16%
|
Defeat It Lives! 21 times | Dank Depths | 16%
|
Defeat Mom's Heart or It Lives! on Hard mode as ??? | Dead Baby | 16%
|
Complete Scat Man (Challenge #36) | Dirty Mind | 16%
|
Defeat Mom's Heart or It Lives! on Hard mode as Jacob and Esau | Double Baby | 16%
|
Defeat The Beast as Tainted Jacob | Esau Jr. | 16%
|
Donate 439 coins to the Greed Donation Machine | Eve holds Razor Blade | 16%
|
Pick up both key pieces in a single run | Filigree Feather | 16%
|
Complete SPEED! (Challenge #22) | Get out of Jail Free Card | 16%
|
Defeat Delirium as Tainted Lost | Ghost Bombs | 16%
|
Earn all Hard mode completion marks as The Lost | Godhead | 16%
|
Complete Blue Bomber (Challenge #23) | Gold Bomb | 16%
|
Defeat Mega Satan as Tainted Keeper | Golden Penny | 16%
|
Defeat Mega Satan as Tainted Jacob | Golden Trinkets | 16%
|
Complete XXXXXXXXL (Challenge #21) | Gold Heart | 16%
|
Defeat Satan as Magdalene | Guardian Angel | 16%
|
Defeat Mom | Have a Heart | 16%
|
Defeat Delirium as The Lost | Holy Card | 16%
|
Complete Boss Rush as Lilith | Immaculate Conception | 16%
|
Defeat Mega Satan and unlock The Negative | I RULE! | 16%
|
Defeat Mother | Isaac's Awakening | 16%
|
Defeat Isaac as The Lost | Isaac's Heart | 16%
|
Defeat The Beast as Tainted Forgotten | Isaac's Tomb | 16%
|
Defeat Ultra Greedier as Tainted Lazarus | Judgement? | 16%
|
Defeat Mother as Keeper | Keeper's Sack | 16%
|
Defeat Isaac as Lazarus | Lazarus' Rags | 16%
|
Defeat Delirium as Tainted Bethany | Lemegeton | 16%
|
Die to your own explosion from Ipecac, Bob's Rotten Head, or a Horf! pill | Lil Spewer | 16%
|
Complete Boss Rush as Apollyon | Locust of Conquest | 16%
|
Defeat Satan as Apollyon | Locust of Pestilence | 16%
|
Defeat Lokii | Loki's Horns | 16%
|
Destroy 100 rocks | Lucky Rock | 16%
|
Complete Aprils Fool (Challenge #32) | Maggy Holds a Pill | 16%
|
Defeat Mother as Jacob and Esau | Magic Skin | 16%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Isaac | Mom's Lock | 16%
|
Use Pandora's Box in Dark Room | Moving Box | 16%
|
Reset 7 times in a row (On Switch/PS4, get a -10 win streak) | Mr. Resetter! | 16%
|
Defeat The Beast as Isaac | Options? | 16%
|
Defeat The Lamb as Lazarus | Pandora's Box | 16%
|
Defeat Isaac as Cain and destroy 10 tinted rocks | PAY TO PLAY | 16%
|
Defeat Mom | PRIDE DAY! | 16%
|
Defeat Mom | Purist | 16%
|
Defeat Mega Satan as Magdalene | Red Baby | 16%
|
Complete The Tank (Challenge #5) | Rune of Ansuz | 16%
|
Complete Ultra Hard (Challenge #34) | Samson Feels Healthy! | 16%
|
Defeat Isaac as Azazel | Satanic Bible | 16%
|
Defeat Mother | Seeing Double | 16%
|
Complete Bloody Mary (Challenge #37) | Sigil of Baphomet | 16%
|
Beat Basement 40 times | Something From The Future | 16%
|
Defeat ??? as 3 different characters | Something wicked this way comes! | 16%
|
Defeat ??? as 6 different characters | Something wicked this way comes+! | 16%
|
Defeat Delirium as Bethany | Star of Bethlehem | 16%
|
Defeat Ultra Greedier as Tainted Samson | Strength? | 16%
|
Defeat The Lamb as Lilith | Succubus | 16%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Samson | Temporary Tattoo | 16%
|
Defeat Ultra Greedier as Tainted Bethany | The Hierophant? | 16%
|
Defeat Ultra Greedier as Tainted Lilith | The High Priestess? | 16%
|
Defeat Ultra Pride or defeat ??? as Judas | The Left Hand | 16%
|
Use XIII - Death 4 times | The Necronomicon | 16%
|
Pick up any 2 items that have the "dead" tag in a single run | The Parasite | 16%
|
Defeat The Beast as Tainted ??? | The Swarm | 16%
|
Have 7 or more red heart containers at one time | The Tank | 16%
|
Donate 33 coins to the Greed Donation machine | Wooden Nickel | 16%
|
Defeat Satan as Cain | A Bag of Bombs | 11%
|
Defeat Isaac as Cain | A Bag of Pennies | 11%
|
Pick up 10 Angel Room items | A Forgotten Horseman | 11%
|
Enter 10 Arcades | A Gamekid | 11%
|
Beat Chapter 6 | Angels | 11%
|
Defeat Mom's Heart 3 times | A Noose | 11%
|
Defeat Mother as Tainted Apollyon | Apollyon's Best Friend | 11%
|
Defeat The Beast as Cain | A Pound of Flesh | 11%
|
Defeat Mother as Tainted Azazel | Azazel's Stump | 11%
|
Defeat Mega Satan and unlock The Negative | Backasswards | 11%
|
Complete Boss Rush as Bethany | Beth's Faith | 11%
|
Defeat Mega Satan as Azazel | Black Baby | 11%
|
Defeat Mega Satan as Tainted Judas | Black Sack | 11%
|
Defeat ??? as Bethany | Blessed Penny | 11%
|
Defeat The Beast as Tainted Cain | Blue Key | 11%
|
Donate 10 coins to the Donation Machine | Blue Map | 11%
|
Destroy 5 rainbow poops | Bozo | 11%
|
Defeat Mega Satan as Judas | Brown Baby | 11%
|
Complete 2 Victory Laps and start a 3rd | Butter! | 11%
|
Defeat ??? as Lilith | Cambion Conception | 11%
|
Defeat ??? as Magdalene | Celtic Cross | 11%
|
Donate to Battery Bums until they pay out with an item 5 times | Charged Penny | 11%
|
Defeat Mega Satan as Tainted ??? | Charming Poop | 11%
|
Defeat Delirium as Tainted Eden | Corrupted Data | 11%
|
Defeat Mega Satan as Tainted Samson | Crane Game | 11%
|
Defeat Mother as Tainted Keeper | Cursed Penny | 11%
|
Defeat The Lamb as Judas | Curved Horn | 11%
|
Earn all Hard mode Completion Marks as Lilith | Dark Baby | 11%
|
Defeat Delirium as Tainted Forgotten | Decap Attack | 11%
|
Defeat Mom's Heart 9 times | Demo Man | 11%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted ??? | Dingle Berry | 11%
|
Defeat Delirium as Eden | Eden's Soul | 11%
|
Defeat Delirium as Magdalene | Eucharist | 11%
|
Defeat Isaac as Eve | Eve's Bird Foot | 11%
|
Complete Boss Rush as Eve | Eve's Mascara | 11%
|
Defeat Mom's Heart 7 times | Experimental Treatment | 11%
|
Defeat Ultra Greedier as Keeper | Eye of Greed | 11%
|
Pick up Rubber Cement 5 times | Flat Stone | 11%
|
Defeat Mega Satan as Tainted Lilith | Fool's Gold | 11%
|
Destroy The Siren's skull after defeating her | Forgotten Lullaby | 11%
|
Defeat Ultra Greed as Eden | GB Bug | 11%
|
Complete The Family Man (Challenge #19), defeat Lokii, and unlock Judas | Glass Cannon | 11%
|
Defeat Mega Satan as Tainted Forgotten | Golden Battery | 11%
|
Donate 500 coins to the Greed Donation Machine | Greedier! | 11%
|
Complete PONG (Challenge #35) | Greed's Gullet | 11%
|
Defeat Mega Satan as Cain | Green Baby | 11%
|
Pick up Blood Clot 10 times | Haemolacria | 11%
|
Defeat Mega Satan as Tainted Lost | Haunted Chest | 11%
|
Defeat Mega Satan as Tainted Eve | Horse Pill | 11%
|
Increase in size 5 times in a single run | Huge Growth | 11%
|
Defeat Hush as Apollyon | Hushy | 11%
|
Defeat Delirium as Tainted Magdalene | Hypercoagulation | 11%
|
Defeat The Beast as Bethany | Jar of Wisps | 11%
|
Defeat Satan as Judas | Judas' Tongue | 11%
|
Complete Cantripped! (Challenge #43) | Justice? | 11%
|
Defeat Satan as Keeper | Keeper holds Store Key | 11%
|
Defeat Isaac, Satan, ???, and Blue Baby as Tainted Keeper | Keeper's Bargain | 11%
|
Complete Onan's Streak (Challenge #29) | Kidney Stone | 11%
|
Pick up 20 Devil Room items | Krampus | 11%
|
Defeat The Beast as Azazel | Lil Abaddon | 11%
|
Defeat Ultra Greed as Isaac | Lil' Chest | 11%
|
Beat Chapter 2 | Lil' Chubby | 11%
|
Defeat The Lamb as Apollyon | Locust of Death | 11%
|
Defeat ??? as Apollyon | Locust of Famine | 11%
|
Defeat Mother as The Lost | Lost Soul | 11%
|
Defeat The Lamb as Isaac | Missing Poster | 11%
|
Pick up 3 "Yes Mother?" items in a single run | Mom's Contact | 11%
|
Defeat The Beast as ??? | Montezuma's Revenge | 11%
|
Unlock Judas and It Lives! | Onan's Streak | 11%
|
Allow Baby Plum to escape instead of defeating her | Plum Flute | 11%
|
Defeat Mom's Heart 11 times | Pokey Mans | 11%
|
Defeat Hush as Magdalene | Purity | 11%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Jacob | RC Remote | 11%
|
Defeat Mega Satan as Tainted Apollyon | Rotten Beggar | 11%
|
Enter Corpse for the first time | Rotten Heart | 11%
|
Have 20 Blue Flies in the same room | Rotten Penny | 11%
|
Defeat Delirium as Cain | Silver Dollar | 11%
|
Complete It's in the Cards (Challenge #14) | SMB Super Fan | 11%
|
Beat Chapter 3 20 times | Something Sticky | 11%
|
Defeat Ultra Greedier as Samson | Stem Cell | 11%
|
Complete Boss Rush as Keeper | Sticky Nickels | 11%
|
Defeat ??? as Lazarus | Store Credit | 11%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Eve | Strange Key | 11%
|
Pick up any 2 items that have the "tech" tag in a single run | Technology Zero | 11%
|
Complete DELETE THIS (Challenge #45) | Temperance? | 11%
|
Defeat ??? as The Lost | The Body | 11%
|
Pick up both key pieces from Angels in one run | The Family Man | 11%
|
Defeat Ultra Greedier as Tainted Keeper | The Hanged Man? | 11%
|
Defeat Ultra Greedier as Tainted Magdalene | The Lovers? | 11%
|
Defeat Ultra Greedier as Tainted Judas | The Magician? | 11%
|
Defeat Satan as The Lost | The Mind | 11%
|
Complete Boss Rush as Azazel | The Nail | 11%
|
Defeat Satan as Eve | The Razor | 11%
|
Defeat Mother as Tainted Lazarus | Torn Card | 11%
|
Pick up 25 Angel Room items | Trisagion | 11%
|
Defeat Mega Satan and unlock The Negative | Ultra Hard | 11%
|
Defeat Satan as Bethany | Urn of Souls | 11%
|
Defeat Ultra Greedier as Tainted Cain | Wheel of Fortune? | 11%
|
Defeat Mom's Heart 4 times | Wire Coat Hanger | 11%
|
Defeat Mega Satan as Tainted Lazarus | Wooden Chest | 11%
|
Defeat Mega Satan as Eden | Yellow Baby | 11%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Judas | Your Soul | 11%
|
Defeat Mother as Magdalene | Yuck Heart | 11%
|
Defeat Ultra Greed as The Lost | Zodiac | 11%
|
Unlock all secrets and endings and pick up every item in Afterbirth | 1001% | 5%
|
Defeat all 5 Harbingers | 7 Seals | 5%
|
Defeat ??? as Azazel | Abaddon | 5%
|
Defeat The Lamb as Cain | Abel | 5%
|
Defeat Isaac as Magdalene | A Cross | 5%
|
Defeat Mother as Tainted Lilith | Adoption Papers | 5%
|
Defeat Mom's Heart 9 times | A Fetus in a Jar | 5%
|
Defeat The Lamb as Bethany | Alabaster Box | 5%
|
Use cards or runes 20 times | Ancient Recall | 5%
|
Defeat Ultra Greedier as Azazel | Bat Wing | 5%
|
Defeat The Beast as Tainted Magdalene | Belly Jelly | 5%
|
Defeat Ultra Greed as Eve | Black Feather | 5%
|
Defeat The Lamb as Eve | Black Lipstick | 5%
|
Defeat Hush as Samson | Blind Rage | 5%
|
Defeat Mother as Lilith | Blood Puppy | 5%
|
Defeat Satan as Samson | Blood Rights | 5%
|
Defeat ??? as Samson | Bloody Penny | 5%
|
Defeat Mother as The Forgotten | Bone Spur | 5%
|
Defeat The Lamb as The Forgotten | Brittle Bones | 5%
|
Pick up 5 familiars in a single run | Buddy in a Box | 5%
|
Complete Beans! (Challenge #13) | Burnt Penny | 5%
|
Donate 68 coins to the Greed Donation machine | Cain holds Paperclip | 5%
|
Defeat ??? as Cain | Cain's Eye | 5%
|
Complete Boss Rush as Cain | Cain's Other Eye | 5%
|
Defeat The Beast as Magdalene | Candy Heart | 5%
|
Defeat Ultra Greed as Magdalene | Censer | 5%
|
Complete Demo Man (Challenge #9) | Chaos Card | 5%
|
Purchase anything from Shops, Devil Rooms, and/or Black Markets 50 times | Coupon | 5%
|
Defeat The Beast as Eve | Cracked Orb | 5%
|
Complete Cursed! (Challenge #10) | Credit Card | 5%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Apollyon | Cricket Leg | 5%
|
Defeat Ultra Greedier as Eve | Crow Heart | 5%
|
Defeat Mom's Heart 11 times and defeat ??? as Eve | Darkness Falls | 5%
|
Defeat Mother as Azazel | Devil's Crown | 5%
|
Defeat Delirium as Eve | Dull Razor | 5%
|
Defeat Hush as Eden | Eden's Blessing | 5%
|
Pick up both Broken Watch and Stop Watch (Doesn't have to be in a single run) | Era Walk | 5%
|
Defeat Mother as ??? | Eternal D6 | 5%
|
Defeat Delirium as Lilith | Euthanasia | 5%
|
Defeat Ultra Greedier as Judas | Eye of Belial | 5%
|
Defeat Hush as Isaac | Fart Baby | 5%
|
Defeat ??? as ??? | Fate | 5%
|
Defeat Hush as ??? | Fate's Reward | 5%
|
Defeat Satan as ??? | Forget Me Now | 5%
|
Defeat Mother as Tainted Jacob | Found Soul | 5%
|
Defeat The Beast as Jacob and Esau | Friend Finder | 5%
|
Defeat Baby Plum 10 times | Fruity Plum | 5%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Cain | Gilded Key | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as Eden | Glitch Baby | 5%
|
Defeat Ultra Greedier as Magdalene | Glyph of Balance | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as Lilith | Goat Head Baby | 5%
|
Defeat Mega Satan as Tainted Cain | Gold Pill | 5%
|
Defeat Isaac as Judas | Guillotine | 5%
|
Recharge using Lil' Batteries 20 times | Hairpin | 5%
|
Defeat Hush as The Forgotten | Hallowed Ground | 5%
|
Defeat Krampus | Head of Krampus | 5%
|
Defeat The Beast as Tainted Eve | Heartbreak | 5%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Magdalene | Holy Crown | 5%
|
Defeat Ultra Greed as Jacob and Esau | Inner Child | 5%
|
Complete Boss Rush as Isaac | Isaac's Head | 5%
|
Defeat The Lamb without picking up hearts, bombs, or keys for the entire run | It's the Key | 5%
|
Defeat ??? as The Forgotten | Jaw Bone | 5%
|
Complete Boss Rush as Judas | Judas' Shadow | 5%
|
Defeat Isaac as Keeper | Keeper holds Wooden Nickel | 5%
|
Defeat The Beast as Keeper | Keeper's Box | 5%
|
Defeat Ultra Greed as Lazarus | Key Bum | 5%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Lost | Kid's Drawing | 5%
|
Defeat Delirium as ??? | King Baby | 5%
|
Get 10 tear rate upgrades in a single run | Lachryphagy | 5%
|
Defeat Mother as Tainted Eve | Lil Clot | 5%
|
Defeat Isaac as Apollyon | Locust of Wrath | 5%
|
Become Beelzebub | Lord of the Flies | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as Isaac | Lost Baby | 5%
|
Defeat Mother as Tainted Cain | Lucky Sack | 5%
|
Destroy 20 Shopkeepers | Lucky Toe | 5%
|
Complete Boss Rush as Magdalene | Maggy's Bow | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as The Forgotten | Marrow | 5%
|
Defeat Hush as Azazel | Maw of the Void | 5%
|
Defeat Ultra Greedier as ??? | Meconium | 5%
|
Defeat Mother as Tainted Magdalene | Mother's Kiss | 5%
|
Defeat ??? as Eden | Mysterious Paper | 5%
|
Defeat Mother as Tainted Judas | Number Magnet | 5%
|
Defeat Ultra Greedier as Lazarus | Plan C | 5%
|
Complete I RULE! (Challenge #26) | Poker Chip | 5%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Forgotten | Polished Bone | 5%
|
Defeat Isaac 5 times | PONG | 5%
|
Beat Chapter 4 without taking damage | Pop! | 5%
|
Defeat Mega Satan as Samson | Rage Baby | 5%
|
Defeat The Beast as Judas | Redemption | 5%
|
Defeat Satan as Jacob and Esau | Red Stew | 5%
|
Complete Computer Savvy (Challenge #16) | Robo-Baby 2.0 | 5%
|
Complete Glass Cannon (Challenge #11) | Rules Card | 5%
|
Defeat Isaac as Lilith | Rune Bag | 5%
|
Defeat ??? as Eve | Sacrificial Dagger | 5%
|
Defeat The Beast as Tainted Lazarus | Salvation | 5%
|
Complete Boss Rush as Samson | Samson's Chains | 5%
|
Defeat The Beast as Tainted Judas | Sanguine Bond | 5%
|
Enter 6 Shops in one run | Schoolbag | 5%
|
Defeat Isaac as The Forgotten | Slipped Rib | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as Apollyon | Smelter | 5%
|
Defeat Mom's Heart 3 times | Solar System | 5%
|
Beat Chapter 2 30 times | Something Cute | 5%
|
Complete Boss Rush as ??? | ???'s Only Friend | 5%
|
Donate 234 coins to the Greed Donation Machine | Special Shopkeepers | 5%
|
Defeat The Beast as The Forgotten | Spirit Shackles | 5%
|
Donate 666 coins to the Greed Donation Machine | Store Key | 5%
|
Donate 20 coins to the Donation Machine | Store Upgrade lv. 1 | 5%
|
Get a 5-win streak in Daily Challenges (They don't have to be consecutive days) | The Marathon | 5%
|
Donate 50 coins to the Donation Machine | There's Options | 5%
|
Defeat Isaac as Jacob and Esau | The Stairway | 5%
|
Defeat The Beast as Tainted Bethany | Vengeful Spirit | 5%
|
Defeat Mega Satan as The Lost | White Baby | 5%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Azazel | Wicked Crown | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as Bethany | Wisp Baby | 5%
|
Sleep in a bed | Wooden Cross | 5%
|
Defeat Mom's Heart or It Lives! on Hard mode as The Lost | -0- Baby | 0%
|
Complete Have a Heart (Challenge #25) | Complete PAY TO PLAY (Challenge #24) | 2 new pills | 0%
|
Defeat Mother as Judas | Akeldama | 0%
|
Defeat an Angel 10 times | Angelic Prism | 0%
|
Become Beelzebub | Angry Fly | 0%
|
Earn all Hard mode Completion Marks as Apollyon | Apollyon Baby | 0%
|
Defeat The Beast as Lazarus | Astral Projection | 0%
|
Defeat Hush as Eve | Athame | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Azazel | Begotten Baby | 0%
|
Earn all Hard mode Completion Marks as Judas | Belial Baby | 0%
|
Defeat Mother as Tainted Bethany | Beth's Essence | 0%
|
Defeat Hush as Judas | Betrayal | 0%
|
Defeat Mega Satan as Lilith | Big Baby | 0%
|
Defeat Mother as Eve | Bird Cage | 0%
|
Defeat 20 Portals | Black Hole | 0%
|
Use Blank Card while holding XIX - The Sun | Blinding Baby | 0%
|
Defeat Delirium as Samson | Bloody Crown | 0%
|
Defeat Satan as Eden | Book of Secrets | 0%
|
Defeat Delirium as The Forgotten | Book of the Dead | 0%
|
Defeat Mega Satan as The Forgotten | Bound Soul | 0%
|
Defeat Satan as Lazarus | Broken Ankh | 0%
|
Defeat Ultra Greed as Apollyon | Brown Nugget | 0%
|
Earn all Hard mode Completion Marks as Isaac | Buddy Baby | 0%
|
Destroy 100 poops | Butter Bean | 0%
|
Complete Pokey Mans (Challenge #33) | Charged Key | 0%
|
Earn all Hard mode Completion Marks as Magdalene | Colorful Baby | 0%
|
Defeat Delirium as Lazarus | Compound Fracture | 0%
|
Play Shell Game or Hell Game 100 times | Counterfeit Coin | 0%
|
Earn all Hard mode Completion Marks as Eden | Cracked Baby | 0%
|
Defeat Ultra Greed as ??? | Cracked Dice | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Eve | Crow Baby | 0%
|
Defeat Mega Satan as Isaac | Cry Baby | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Magdalene | Cute baby | 0%
|
Defeat Ultra Greedier as The Lost | Dad's Lost Coin | 0%
|
Defeat Ultra Greedier as The Forgotten | Dad's Ring | 0%
|
Defeat Satan as Azazel | Daemon's Tail | 0%
|
Take 25 Devil Deals | Death's List | 0%
|
Defeat ??? as Keeper | Deep Pockets | 0%
|
Defeat Delirium as Azazel | Demon Prince's Crown | 0%
|
Defeat Hush as Bethany | Divine Intervention | 0%
|
Complete Boss Rush as The Forgotten | Divorce Papers | 0%
|
Destroy doors and Secret Room walls 50 times | Door Stop | 0%
|
Earn all Hard mode Completion Marks as Lazarus | Dripping Baby | 0%
|
Defeat Ultra Greedier as Lilith | Duality | 0%
|
Defeat The Beast as Samson | Empty Heart | 0%
|
Defeat Hush as Lazarus | Empty Vessel | 0%
|
Defeat The Beast as Eden | Everything Jar | 0%
|
Defeat Ultra Greed as Cain | Evil Eye | 0%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Bethany | Expansion Pack | 0%
|
Pick up The Battery, 9 Volt, and Car Battery (Doesn't have to be in a single run) | Extension Cord | 0%
|
Defeat Little Horn 20 times | Fast Bombs | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Samson | Fighting Baby | 0%
|
Defeat Ultra Greed as The Forgotten | Finger Bone | 0%
|
Donate 999 coins to the Greed Donation Machine | Generosity | 0%
|
Defeat Ultra Greedier as Jacob and Esau | Genesis | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Cain | Glass Baby | 0%
|
Defeat Mega Satan as Bethany | Glowing Baby | 0%
|
Get a 3-win streak | Hat trick! | 0%
|
Earn all Hard mode Completion Marks as ??? | Hive Baby | 0%
|
Defeat Mother as Tainted Forgotten | Hollow Heart | 0%
|
Earn all Hard mode Completion Marks as Bethany | Hope Baby | 0%
|
Defeat The Beast as The Lost | Hungry Soul | 0%
|
Defeat Mega Satan as Jacob and Esau | Illusion Baby | 0%
|
Defeat Isaac as Isaac | Isaac's Tears | 0%
|
Pick up any 2 items that have the "battery" tag in a single run | Jumper Cables | 0%
|
Defeat The Lamb as Keeper | Karma | 0%
|
Defeat Hush as Keeper | Keeper holds Penny | 0%
|
Defeat The Beast as Tainted Samson | Larynx | 0%
|
Beat Chapter 3 without taking damage | Leprosy | 0%
|
Defeat Mega Satan as Eve | Lil' Baby | 0%
|
Defeat Mother as Apollyon | Lil Portal | 0%
|
Pick up any 2 items with the "syringe" tag in a single run | Little Baggy | 0%
|
Beat any Chapter except Chapter 1 on one half heart (Can use The Lost) | Living on the edge | 0%
|
Defeat Mega Satan as Lazarus | Long Baby | 0%
|
Donate 2 coins to the Greed Donation Machine | Lucky Pennies | 0%
|
Defeat Mother as Isaac | Meat Cleaver | 0%
|
Spend 40+ coins in a single Shop | Member Card | 0%
|
Defeat Ultra Greedier as Eden | Metronome | 0%
|
Defeat Mother as Tainted Eden | Modeling Clay | 0%
|
Defeat Mega Satan as Apollyon | Mort Baby | 0%
|
Defeat Ultra Greed as Judas | My Shadow | 0%
|
Spawn 3 charmed enemies in the same room | Mystery Egg | 0%
|
Destroy 500 rocks | Mystery Gift | 0%
|
Defeat The Lamb as Eden | Mystery Sack | 0%
|
Defeat Hush | New Area | 0%
|
Defeat Mega Satan as Keeper | Noose Baby | 0%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Eden | Nuh Uh! | 0%
|
Destroy 10 Battery Bums | Old Capacitor | 0%
|
Complete a Victory Lap | Once More with Feeling! | 0%
|
Earn all Hard mode Completion Marks as Cain | Picky Baby | 0%
|
Defeat Satan as The Forgotten | Pointy Rib | 0%
|
Complete Baptism by Fire (Challenge #38) | Purgatory | 0%
|
Earn all Hard mode Completion Marks as Samson | Revenge Baby | 0%
|
Defeat Ultra Greed as Keeper | Rib of Greed | 0%
|
Defeat Mother as Tainted ??? | Ring Cap | 0%
|
Defeat Ultra Greedier as Cain | Sack of sacks | 0%
|
Take 50 Devil Deals | Sacrificial Altar | 0%
|
Earn all Hard mode Completion Marks as keeper | Sale Baby | 0%
|
Defeat The Lamb as Samson | Samson's Lock | 0%
|
Defeat Satan as Lilith | Serpent's Kiss | 0%
|
Defeat Delirium as Judas | Shade | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Judas | Shadow Baby | 0%
|
Collect every entry in the bestiary | Sin collector | 0%
|
Earn all Hard mode Completion Marks as Jacob and Esau | Solomon Baby | 0%
|
Defeat Isaac 10 times | Something Icky | 0%
|
Defeat Ultra Greed as Bethany | Soul Locket | 0%
|
Donate 14 coins to the Greed Donation Machine | Special Hanging Shopkeepers | 0%
|
Beat Chapter 1 without taking damage | Sprinkler | 0%
|
Defeat The Lamb as ??? | ???'s Soul | 0%
|
Donate 100 coins to the Donation Machine | Store Upgrade lv. 2 | 0%
|
Donate 200 coins to the Donation Machine | Store Upgrade lv. 3 | 0%
|
Donate 600 coins to the Donation Machine | Store Upgrade lv. 4 | 0%
|
Defeat The Beast as Tainted Keeper | Strawman | 0%
|
Complete BRAINS! (Challenge #27) | Stud Finder | 0%
|
Earn all Hard mode Completion Marks as Azazel | Sucky Baby | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Keeper | Super Greed Baby | 0%
|
Defeat Delirium as Jacob and Esau | Suplex! | 0%
|
Defeat Mother as Tainted Samson | Swallowed M80 | 0%
|
Complete Slow Roll (Challenge #15) | Swallowed Penny | 0%
|
Defeat Hush as The Lost | Sworn Protector | 0%
|
Beat Chapter 2 without taking damage | Telekinesis | 0%
|
Defeat The Lamb | The gate is open! | 0%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Lilith | The Twins | 0%
|
Defeat Mother as Lazarus | Tinytoma | 0%
|
Defeat Isaac, Satan, ???, and The Lamb as Tainted Lazarus | Torn Pocket | 0%
|
Pick up 50 items in a run (Can be duplicates) | U broke it! | 0%
|
Complete Boss Rush as Eden | Undefined | 0%
|
Defeat Ultra Greedier as Bethany | Vade Retro | 0%
|
Defeat Hush as Jacob and Esau | Vanishing Twin | 0%
|
Earn all Hard mode Completion Marks as Eve | Whore Baby | 0%
|
Defeat The Beast as Apollyon | Worm Friend | 0%
|
Defeat Mom's Heart or It Lives! on Hard mode as Lazarus | Wrapped Baby | 0%
|
Defeat The Lamb in under 20 minutes | ZIP! | 0%
|
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