Biochemistry

Quiz by mblessing21
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Last updated: April 24, 2024
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First submittedApril 24, 2024
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1. Which of the following is not an organelle?
Nucleus
Plasma membrane
Golgi complex
Mitochondria
Chloroplast
2. Metabolism is best defined as the ___________.
Reactions that synthesize and degrade molecules in living cells
Reactions of living cells
Reactions that degrade molecules in living cells
Conversion of food molecules to energy
Reactions that synthesize large molecules in living cells
3. The following is an example of which reaction class? CH3Br + HSCH2CH(NH2)COOH ---> CH3SCH2CH(NH2)COOH + Br- + H+
Isomerization
Elimination
Oxidation/Reduction
Substitution
Addition
4. Which of the following is not one of the 6 most common elements found in life?
Hydrogen
Phosphorus
Nitrogen
Oxygen
All of the above are basic elements of life
5. Which of the following amino acids contain a hydrophobic side chain?
Leucine
Glutamic Acid
Aspartic Acid
Arginine
Glutamine
6. Which of the following is not true of life?
Life is complex and dynamic
All living things produce energy using mitochondria
Life is information based
Life adapts and evolves
Life is cellular
7. Which of the following is not an example of a macromolecule?
Amino Acid
Polysaccharide
Nucleic acid
Protein
Enzyme
8. The excluded volume of a cell varies between _______ and ________%.
5-10
40-50
20-40
0-5
10-20
9. Which of the following is present only in prokaryotic cells?
Endoplasmic reticulum
None of the above is correct
Nucleus
Nucleolus
Plasma membrane
10. Which of the following is a hydronium ion?
OH-
HOOH
H4O++
CH3OH2+
H3O+
11. The most important buffer in blood?
Phosphate buffer
Tartrate buffer
Carbonate/bicarbonate buffer
Protein buffer
Lactate buffer
12. Which of the following is not a class of amino acid?
Basic
Nonpolar and neutral
Asymmetric
Acidic
Polar and neutral
13. The amino acid sequence of a polypeptide is referred to as _________ structure.
Primary
Tertiary
Quaternary
Peptide
Secondary
14. The overall three-dimensional structure of a polypeptide is referred to as _________ structure.
Secondary
Peptide
Tertiary
Quaternary
Primary
15. B-pleated sheets are associated with what level of protein structure?
Tertiary
Primary
Quaternary
Secondary
Peptide
16. Which of the following classes of enzymes catalyze reactions involving the cleavage of bonds by the addition of water?
Hydrolase
Ligase
Transferase
Lyase
Isomerase
17. In the Lineweaver-Burk double reciprocal plot the slope is equal to ____________.
1/V
-1/Km
1/[S]
1/Vmax
Km/Vmax
18. Catalysts are effective because they ___________.
A. decrease the rate of the reverse reaction
B. decrease the activation energy of a reaction
D. increase the energy released during a reaction
C. stabilize the transition state
E. both B and C are correct
19. In addition to serine and aspartate which of the following amino acids is a member of the serine triad?
Glycine
Histidine
Glutamine
Threonine
Tyrosine
20. Which of the following sugars contains a B-1,4-linkage?
Amylose
Glucose
Cellulose
Maltose
Sucrose
21. In glycoproteins carbohydrate is most often linked to threonine, asparagine or ___________.
aspartic acid
serine
valine
lysine
tyrosine
22. Lactose intolerance arises from ____________.
the inability of intestinal enzymes to cleave the lactose
bacteria in the intestine that produce toxic metabolites
an allergic reaction to glucose
a sensitivity to galactose
a sensitivity to glucose
23. The principal structural carbohydrate of plants is ______________.
Starch
Glycogen
Cellulose
Amylose
Xylulose
24. Which of the following amino acids is not one of the twenty standard amino acids?
Phenylalanine
Tyrosine
Arginine
Cystine
Glycine
25. Which of the following is a hydrophobic amino acid?
Glycine
Both C and D are hydrophobic
Serine
Phenylalanine
Lysine
26. Which of the following amino acids would be classified as a nonstandard amino acid?
Lysine
Tyrosine
Glycine
Arginine
Cystine
27. Why is the peptide bond stronger than the ester bond?
Increased basicity of nitrogen
Resonance stabilization of the amide bond
Size of nitrogen atom compared to the oxygen atom
Greater electronegativity of oxygen
Greater electronegativity of nitrogen
28. Which of the following interactions does not stabilize tertiary structure?
Covalent bonds
None of the above
Electrostatic interactions
Hydrogen bonds
Hydrophobic interactions
29. Which of the following is not a class of amino acid?
Acidic
Asymmetric
Basic
Nonpolar and neutral
Polar and neutral
30. Which is more stable and why? i. anti-parallel B-sheets ii. parallel B-sheets iii. there is no stability difference iv. the H-bond donors and acceptors line up straight across from each other v. the H-bond donors and acceptors are slightly offset from each other
i, v
i, iv
i, ii, iii
ii, v
ii, iv
31. Double headed curved arrows show the movement of what?
Two e-'s
Functional groups
Two protons
A single proton
Single e-
32. Fatty acids are referred to as __________ groups.
Acetyl
Acyl
Isopentenyl
Prenyl
Isoprenoid
33. The double bonds in naturally occurring fatty acids are usually ____________ isomers.
Trans
Essential
Cis
Both cis and trans
Nonessential
34. Phospholipids are
A. Structural components of membranes
D. All of the above are correct
C. Rich energy sources
E. Both A and B are correct
B. Surface active agents
35. Which of the following molecules is not a lipid?
Isoprenoids
Fatty acids
Waxes
All of the above are lipids
Steroids
36. Energy requiring transport mechanisms include
A. Diffusion
B. Facilitate diffusion
C. Primary active transport
D. Both A and C are correct
E. Both A and B are correct
37. FADH2 is a product of which of the following reactions?
Succinyl-CoA --> Succinate
Succinate --> Malate
Malate --> Oxaloacetate
Pyruvate --> Acetyl CoA
Succinate --> Fumarate
38. The regulated enzymes of the citric acid cycle include _____________.
Fumarase
Malate dehydrogenase
Citrate lyase
a-Ketoglutarate dehydrogenase
Succinate thiokinase
39. Redox potential is best defined as
The tendency of one species to gain electrons
None of the above is correct
The entropy of a reaction expressed as a voltage difference
The tendency of a species to gain or lose electrons
The tendency of one species to lose electrons
40. Which of the following reacts with Acetyl-CoA to form citrate?
Oxaloacetate
Succinate
Fumarate
Malate
a-Ketoglutarate
41. Which of the following reactions requires GDP?
Malate --> Oxaloacetate
Fumarate --> Malate
Citrate --> Isocitrate
Succinyl-CoA --> Succinate
a-Ketoglutarate --> Succinyl-CoA
42. Which of the following is required for the conversion of UDP-glucose to glycogen?
A. Branching enzyme
C. Glucose phosphorylase
B. Glycogen synthase
D. Debranching enzyme
E. Both A and B are correct
43. Glucose-6-phosphate is a substrate in which of the following processes?
D. Photosynthesis
C. Glycogenolysis
Both A and B are correct
A. Gluconeogenesis
B. Glycolysis
44. In glycolysis __________ net moles of ATP are produce per mole of glucose consumed.
one
two
three
four
five
45. In glycolysis _________ moles of NADH are produced per mole of glucose consumed.
one
two
three
four
five
46. The presence of which of the following molecules indicates that the cell has sufficient energy reserves?
A. ATP
B. Citrate
C. ADP
D. F1,6P
E. Both A and B are correct
47. Which of the following enzymes catalyzes an irreversible process?
Pyruvate kinase
Aldolase
Enolase
Phosphoglycerate mutase
Glyceraldehyde-3-phosphate dehydrogenase
48. In anaerobic organisms pyruvate is used to regenerate cellular __________.
NADP+
FADH
FAD
NAD+
ADP
49. Which of the following describes the low of genetic information as stated in the central dogma of molecular biology?
RNA --> Protein --> DNA
DNA --> RNA --> Protein
DNA --> Protein --> RNA
Protein --> RNA --> DNA
None of the above is correct
50. The DNA "backbone" is composed of
An amide bond between deoxyribose and a nitrogenous base
A glycosidic bond between deoxyribose and a nitrogenous baes
A phosphodiester bond between 3' and 5' hydroxyl groups of adjacent deoxyribose residues
A phosphodiester bond between 2' and 5' hydroxyl groups of adjacent deoxyribose residues
None of the above is correct
51. Which of the following does not contribute to the noncovalent interactions that stabilize the helical strands of DNA?
Hydrophobic interactions
Phosphodiester bonds
Hydrogen bonds
Base stacking
Hydration
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