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Developmental and Stem Cell Biology Quiz

Stem Cells are very interesting cells. Try to answer these questions correctly
Quiz by Smarx
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Last updated: December 26, 2022
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First submittedDecember 26, 2022
Times taken10
Average score46.7%
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1. The zygote is
Multipotent ✓
Unipotent ✓
Totipotent ✓
Pluripotent ✓
2. Pluripotent Stem Cells resemble the cells of the
Zygote ✓
Epiblast ✓
Trophectoderm ✓
Hypoblast ✓
3. OCT4, SOX2, c-MYC, and KLF4 are also known as
The Gurdon Factors ✓
The Smith Factors ✓
The Takashima Factors ✓
The Yamanaka Factors ✓
4. These factors are used to make
IVF embryos ✓
Hematopoietic stem cells ✓
Induced pluripotent stem cells ✓
Embryonic stem cells ✓
5. These factors are
Cytokines ✓
Transcription factors ✓
Antibodies ✓
Chromatin Regulators ✓
6. Naive Pluripotent Stem Cells resemble the cells of
the cells of the morula ✓
the pre-implantation epiblast ✓
the post-implantation epiblast ✓
the blastocyst ✓
7. Primed Pluripotent Stem Cells resemble the cells of
the pre-implantation epiblast ✓
the post-implantation epiblast ✓
the blastocyst ✓
the cells of the morula ✓
8. A blastocyst embryoid (embryo organoid/ 3D-stem cell based embryo-model) is also called
A Blastoid ✓
A Humanoid ✓
An embryoid body ✓
An embryonic spheroid ✓
9. Pluripotent stem cells can give rise to
All foetal cell lineages ✓
All extra-embryonic cell lineages ✓
All cell lineages ✓
All embryonic cell lineages ✓
10. The process of developmental maturation/specialization of a cell is called
Differentiation ✓
Reprogramming ✓
Cis-differentiation ✓
Trans-differentiation ✓
11. The process of developmental rejuvenation is called
Differentiation ✓
Cis-differentiation ✓
Trans-differentiation ✓
Reprogramming ✓
12. The process of conversion of one cell-type to the other without developmental rejuvenation is called
Reprogramming ✓
Cis-differentiation ✓
Trans-differentiation ✓
Differentiation ✓
13. XX/female naive pluripotent stem cells are hallmarked by
Maternal X-chromosome inactivation ✓
Random X-chromosome inactivation ✓
Two active X-chromosomes ✓
Paternal X-chromosome inactivation ✓
14. Conrad Waddington famously compared the cellular developmental process to
Marbles rolling down a hill ✓
A river flowing through a valley ✓
Balls falling on pins ✓
A person walking through a forest ✓
15. What is a stem cell?
A cell that can give rise to other cells ✓
A cell that can proliferate and give rise to other cells ✓
A cell that can divide ✓
A cell that can self-renew and give rise to other cells ✓
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