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CW2 MCQ

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Quiz by doughball
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Last updated: April 26, 2023
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First submittedJanuary 7, 2023
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1. The cytopathic effect refers to structural changes in host cell caused by viral invasion. What type of cytopathic effect is exhibited by Adenovirus?
Cytocidal ✓
Acidophilic inclusion bodies in the cytoplasm ✓
Basophilic inclusion bodies in the cytoplasm ✓
Cell fusion ✓
2. Viruses interact with cell death machinery differently in order to promote the infection process. Some viruses do this by either reducing and/or increasing cell death. Which of the following acts solely through increasing cell death?
Herpesviruses ✓
Poxviruses – Vaccina virus ✓
Retroviruses – HIV ✓
Baculoviruses ✓
3. Which of the following is not a major mode of action exhibited by exotoxins?
Enzymatic lysis ✓
Pore formation ✓
Inhibition of protein synthesis ✓
Injection of a secretory molecule into a host cell ✓
4. Type III and Type IV secretion systems are exhibited by bacterial pathogens. Which of the following statements best describes a type IV secretion system?
Injection of a secretory module into a host cell ✓
Requires contact between the bacterial cell and the host cell – molecules can be both transported and received. ✓
Continuous stimulation by excitatory transmitter ✓
Hydrolyses phosphorylcholine in the cell membrane ✓
5. Some exotoxins exhibit a two-component system (A-B). Which of the following best describes the function of the toxin B subunits?
The B subunit(s) negotiate entry to the host cell ✓
The B subunit(s) internalise into the host cell ✓
The B subunit(s) increase adenylate cyclase activity in the host cell ✓
The B subunit(s) can inactivate elongation factor-2 in the host cell ✓
6. Entamoeba histolytica causes diarrhoea in the host. What is its main mechanism of action?
Increased Cl- secretions ✓
Reduced Na+ absorption ✓
Increased paracellular permeability ✓
Reduced H2O adsorption ✓
7. Which phrase best defines the term Specificity as applied to a diagnostic test in the Clinical Microbiology laboratory?
The ability to designate an individual who does not have a disease as negative. ✓
The ability to designate an individual with disease as positive. ✓
The ability to identify difficult to culture organisms. ✓
The ability to differentiate between members of closely related species ✓
8. The catalase test is used to:
Measure bacterial metabolism under anaerobic conditions. ✓
Differentiate between the genus Staphylococcus and Streptococcus. ✓
Measure sugar fermentation by the Enterobacteriaceae. ✓
Differentiate between the genus Clostridium and Bacillus. ✓
9. “a chemical compound, itself without colour, that can be transformed into a coloured compound, or can react with another material to form a coloured compound” is known as a:
Chrominance ✓
Hue ✓
Chromogen ✓
Wavelength ✓
10. What is not an ESKAPE pathogen?
klebsiella pneumoniae, ✓
acinetobacter baumannii ✓
pseudomonas aeruginosa ✓
streptococcus pneumoniae ✓
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