Statistics for Drug Interactions

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General Stats

This quiz has been taken 4 times
The average score is 4 of 15

Answer Stats

Hint	Answer	% Correct
Does a competetive antagonist have efficacy?	No	100%
How many membrane spanning alpha helices do G protein coupled receptors have?	7	50%
Whereas what is the term used to describe the degree to which a molecule has a tendency to bind to another?	Affinity	50%
What is the word used to describe, the relationship between the amount of receptor occupied by a drug and the size of the response produced?	Efficacy	50%
When a competetive antagonist is added, what direction is an agonists log concentration/response curve shifted in?	Right	50%
What is the name given to the concentration of agonist that causes 50% of the maximum responce?	EC50	25%
What receptor is benzilylcholine mustard an antagonist of?	Muscarinic	25%
What in equations is used to represent the maximal of this type of binding?	Bmax	0%
Which membrane bound protein kinase does diacylglycerol (DAG) stimulate?	C	0%
What toxin effects G protein coupled receptors by causing ADP-ribosylation of alpha-s, inhibiting GTPase activity keeping adenylyl cyclase activated?	Cholera	0%
What is the name given to the answer from this equation. (concentration of agonist with competitive antagonist required to get set response/concentration of agonist without antagonist getting the same response)?	Dose ratio	0%
What is used to represent the concentration of unlabelled drug required to inhibit 50% of specific binding of a radioligand?	IC50	0%
What technique allows recording of the behaviour of a single receptor?	Patch-clamp	0%
The binding of a radioligand (total binding) is made up of two parts, what is the saturable component?	Specific binding	0%
What is the name of a sequence of experiments used to determine the strength of a group of structurally similar compounds?	Structure activity series	0%

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