Drug Interactions

What is the word used to describe, the relationship between the amount of receptor occupied by a drug and the size of the response produced?

Whereas what is the term used to describe the degree to which a molecule has a tendency to bind to another?

When a competetive antagonist is added, what direction is an agonists log concentration/response curve shifted in?

Does a competetive antagonist have efficacy?

What is the name of a sequence of experiments used to determine the strength of a group of structurally similar compounds?

What is the name given to the concentration of agonist that causes 50% of the maximum responce?

The binding of a radioligand (total binding) is made up of two parts, what is the saturable component?

What in equations is used to represent the maximal of this type of binding?

What is the name given to the answer from this equation. (concentration of agonist with competitive antagonist required to get set response/concentration of agonist without antagonist getting the same response)?

What is used to represent the concentration of unlabelled drug required to inhibit 50% of specific binding of a radioligand?

What receptor is benzilylcholine mustard an antagonist of?

What technique allows recording of the behaviour of a single receptor?

How many membrane spanning alpha helices do G protein coupled receptors have?

What toxin effects G protein coupled receptors by causing ADP-ribosylation of alpha-s, inhibiting GTPase activity keeping adenylyl cyclase activated?

Which membrane bound protein kinase does diacylglycerol (DAG) stimulate?