Statistics for Synaptic plasticity references

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General Stats

This quiz has been taken 12 times
The average score is 9 of 34

Answer Stats

Hint	Author	Year	Methods	% Correct
Spatial pre-training in another maze ameliorated effects of above experiment	Bannerman	1995		100%
Application of DA can convert LTD to LTP or reverse LTD depending on timing	Brzosko	2015	Schaffer-collateral CA1 pathway	100%
Calcium transients increased significantly after LTP induction	Emptage	2003	Calcium transients as indicators of release probability	100%
10ms delay in somatic current injections could incur LTD or LTP depending on pairing (post-pre or pre-post)	Markram	1997	Somatic current injection into bidirectionally connected cells	100%
NMDAR-dependent LTP is required for associative spatial memory acquisition	Morris	1986	Mice, NMDAR antagonists	100%
Specific cells fired maximally when mouse is in specific parts of the environment	O'Keefe	1971		100%
Most SC-CA1 have coexpression of NMDAR and AMPAR	Racca	2010	Immunogold NMDAR/AMPAR labelling	100%
AMPARs seen redistributed to dendritic spine surfaces	Shi	1999	GluR-1-GFP, electron microscopy	100%
STDP in xenopus retinotectal synaptic circuit	Zhang	1998		100%
NMDAR blocker prevented LTP	Collingridge	1983	AP-5 applied in SC-CA1 pathway (rats)	0%
STDP in converging inhibitory and excitatory inputs	D'amour	2015	IPSCs/ EPSCs paired with postsynaptic APs respectively	0%
When GluR1 AMPARs coexpressed with CaMKII, increased conductance	Derkrach	1999	Patch-clamp recordings	0%
PKC inhibitor expressed under Purkinje-specific promoter in transgenic mice--> attenuated LTD, VOR adaptation impaired	De Zeeuw	1998		0%
Purkinje-specific PKG KO in mice led to inability to induce LTD and impaired VOR adaptation	Feil	2003		0%
A peptide preventing AMPAR internalisation blocked LTD induction and led to deficits in object recognition in rats	Griffiths	2008		0%
No change in LTP when TTX applied to soma and axon	Hardie	2009	Stratum radiatum	0%
Isolated NMDAR-only cells; found AMPAR-EPSCs after LTP induction	Isaac	1995		0%
Atypic PKC inhibitor returned EPSP to baseline after LTP induction	Ling	2005		0%
Activation of postsynaptic CaMKII sufficient to induce LTP	Lledo	1995	Postsynaptic injection of preactivated CaMKII monomers	0%
EGTA (calcium chelator) blocked LTP	Lynch	1983		0%
Intracellular photolysis of calcium caging compound was enough to induce LTP	Malenka	1988		0%
CaMKII not required for LTP maintenance	Malinow	1989	CaMKII inhibitor added after induction of LTP	0%
STDP in the pre-post pairing of place cells	Meha	1997	Mice trained to run unidirectionally, specific cells fired in sequence	0%
Dendritic spikes are required for LTP	Remy	2007	TTX applied to soma, dendritic spikes recorded in neurons displaying LTP	0%
GluA1 -/- mice have large reductions in measures of spatial and directional selectivity	Resnik	2012	Radial maze--> decreased peformance	0%
Transgenic mice models with AMPAR internalisation defects attenuated LTD, although normal basic motor functions and no impairment of VOR adaptation	Schonewille	2011		0%
Selective destruction of climbing fibres abolished NO responses	Shibuki	1991	NO probe	0%
Inhibition of CaMKII prevents induction of LTP	Silva	1992	CaMKII inhibitory peptide, mice with loss-of-function CaMKII mutation	0%
Decreased performance in a Morris water maze when LTP could not be induced, due to hippocampus-selective GluN1 KO	Tsien	1996		0%
STDP can influence sensory receptive field	Vislay-Meltzer	2006	Mapped receptive fields of xenopus tectal neurons, flashes of light on retina paired with injection of somatic current	0%
PKMzeta KO mice had normal LTP	Volk	2013		0%
STDP in inhibitory GABAergic synapses	Woodin	2008		0%
Attenuated LTD by perfusing Purkinje cells with peptides interfering with PICK1/GluR interactions	Xia	2000		0%
LTP increases transmitter release	Zakharenko	2003	FM1-43 dye (becomes fluorescent when integrated with membrane phospholipids	0%