Diseases A to Z

Guess the disease based on the clues. Use the most common name for the disease.

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Last updated: July 27, 2016

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First submitted	July 27, 2016
Times taken	98
Average score	26.9%
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Letter	Hint	Disease
A	Adrenal glands do not produce enough hormones	Addison disease
B	Thiamine/Vitamin B1 insufficiency	Beriberi
C	Spread by insects in South and Central America, caused by parasite Trypanosoma cruzi	Chagas disease
D	A bacterial infection that can be prevented by the DTap or Tdap vaccines	Diphtheria
E	A common brain disorder that causes repeated chronic sezures	Epilepsy
F	Presents with rheumatoid arthritis, swollen spleen, low white blood cell count, and proneness to infections	Felty syndrome
G	Stomach's contents leak into esophagus and cause erosion with severe heartburn; common	Gastroesophageal reflux disease
H	Genetic disorder that causes neurons in the brain to degenerate, often causing chorea-like movements	Huntington disease
I	Common skin infection caused by streptococcus or staphylococcus	Impetigo
J	Autoimmune illness causing joint pain and swelling in children	Juvenile rheumatoid arthritis
K	XXY chromosomes causing both male and female external characteristics	Klinefelter syndrome
L	Cancer of the white blood cells; begins in the bone marrow	Leukemia
M	An autoimmune disorder that causes weakness in muscles and the nerves that control them	Myasthenia gravis

Letter	Hint	Disease
N	A gangrene-causing infection that rapidly degrades the mucous membranes of the mouth and/or genitals; common in very malnourished, young children	Noma
O	Calcium depletion causes bones to become more brittle and prone to fracture; common in post-menopausal women	Osteoporosis
P	A deficiency in niacin/vitamin B3/nicotinic acid or tryptophan	Pellagra
Q	Extremely rare infection caused by Coxiella burnetti, resulting in fever, cough, nausea, and fatigue	Q fever
R	Softening and weakening of the bones caused by a deficiency in vitamin D or calcium	Rickets
S	Usually a tuberculosis-caused infection resulting in the swelling of lymph nodes in the neck and other areas	Scrofula
T	Genetic blood disorder that produces abnormal hemoglobin; mainly affects those of Mediterranean and East Asian descent	Thalassemia
U	An inflammatory bowel disease causing painful irritation and swelling in the colon and rectum; often associated with weakened immunity	Ulcerative colitis
V	Loss of brown pigment from areas of the skin resulting in white patches	Vitiligo
W	A defect in the heart caused by an excess electrical pathway; results in tachycardia and arrythmia	Wolff-Parkinson-White syndrome
X	Patches or nodules on the skin caused by fat buildup in areas under the skin's surface	Xanthoma
Y	Virus spread by mosquitoes; causes fever, nausea, and vomiting	Yellow fever
Z	Overproduction of the gastrin hormone resulting in abdominal pain and diarrhea	Zollinger-Ellison syndrome

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