Statistics for P+P Part A's 6

Click here to take the quiz!

General Stats
Answer Stats
Score Distribution
Your Score History

General Stats

This quiz has been taken 0 times
The average score is 0 of 97

Answer Stats

Question	Answer	% Correct
The interstitial fluid volume is	10L	0%
Systemic arterial blood pressure (mm Hg)	120/80	0%
Action potential conduction velocity in the largest myelinated nerve fibre is	120m/s	0%
Normal volume of anatomic dead space	150ml	0%
The mean pressure in the main pulmonary artery is	15mmHg	0%
The clearance of gentamicin in a 60 kg woman is 5 L/hour. Calculate the dose to be given by intravenous injection every 8 hours to achieve a mean steady-state concentration (Css) of 4 mg/L.	160mg	0%
When exercising vigorously the maximum heart rate (beats per min; bpm) can reach	180bpm	0%
The normal glomerular filtration rate (GFR) is	180L/day	0%
The total transcellular fluid volume is	1L	0%
Tissue PO2 can be as low as	1mmHg	0%
Pulmonary arterial blood pressure (mm Hg)	20/10	0%
Because of deteriorating renal function the half-life in this patient increases from 2 hours to 12 hours but the original dose is maintained. What new mean steady-state concentration will be reached under these changed circumstances?	24mg/L	0%
Basal oxygen consumption	250ml/min	0%
What is the typical concentration of plasma bicarbonate?	25mM	0%
The intracellular fluid volume is	28L	0%
Normal plasma osmolarity is	290mOsm	0%
The action potential in ventricular myocytes normally has an approximate duration of	300ms	0%
One factor opposing filtration is the glomerular capillary colloid osmotic pressure which is	32mmHg	0%
The extracellular plasma volume is	3L	0%
The PO2 in a red blood entering a pulmonary capillary	40mmHg	0%
The total body fluid volume is	42L	0%
What is the typical concentration of plasma glucose (fasting)?	4mM	0%
serotonin	5-hydroxytryptamine receptors	0%
Resting cardiac output	5L/min	0%
One factor favouring filtration is the glomerular hydrostatic pressure which is	60 mmHg	0%
Ventilation (at rest)	6L/min	0%
The presence of haemoglobin in normal arterial blood increases its oxygen concentration by how many times?	70	0%
Normal blood pH (arterial) is	7.4	0%
The TWO main mechanisms underlying bradycardia are	a decrease in cAMP; potassium channel activation	0%
cortisol	adrenal cortex	0%
Glucagon is synthesised in ... cells	alpha	0%
Insulin secretion is stimulated by	amino acids	0%
growth hormone	anterior pituitary	0%
A clinical use of a voltage-gated K+ channel blocker is	antidysrhythmic	0%
What does the P wave represent?	atrial depolarisation	0%
What might be the cause of the altered activity in Trace B?	atrio-ventricular block	0%
A competitive antagonist at the muscarinic neuroeffector junction	atropine	0%
Insulin is produced by the ... cells of the pancrease	beta	0%
Most of the carbon dioxide transported in the blood is in the form of	bicarbonate	0%
An increase in ... increases the oxygen affinity of haemoglobin	carbon monoxide added to blood	0%
A blocker of noradrenaline uptake into nerve terminals	cocaine	0%
Regarding the rate of rise of the cardiac action potential, local anaesthetics will	decrease it	0%
Strong activation of renal sympathetic nerves	decreases GFR	0%
If the extracellular potassium concentration is doubled, what happens to the resting nerve cell membrane potential?	depolarised	0%
Loss of sympathetic nerve activity will produce	diarrhoea	0%
Blockade of cholinesterase will produce	diarrhoea	0%
In general, for a given clearance the rate of elimination of a drug will vary	directly with the plasma drug concentration	0%
Muscarinic receptors are found in	endothelial cells	0%
NA is synthesised outside the vesicle in nerve terminals and then transported into the vesicle.	false	0%
The upstroke of the action potential in skeletal muscle is usually blocked by calcium channel blockers.	false	0%
Sarcomeres are poorly developed in skeletal muscle.	false	0%
Once released the action of NA is terminated by tyrosine hydroxylase.	false	0%
Released NA acts on muscarinic M3 receptors in bladder smooth muscle.	false	0%
Smooth muscle of the gastrointestinal tract is directly innervated mainly by sympathetic nerves	false	0%
NA is released from preganglionic sympathetic nerves.	false	0%
Sympathetic nerves innervate the motor endplate in skeletal muscle	false	0%
Parasympathetic nerves innervate the motor endplate in smooth muscle	false	0%
The endplate potential is initiated by the actions of acetylcholine released from somatic motor nerves acting at muscarinic M3 receptors.	false	0%
Histamine stimulates the secretion of	gastric acid	0%
Give a metabolic function that the lung does not perform	generating erythropoietin	0%
This secretion is by action at	H2 receptors	0%
A blocker of autonomic ganglia receptors	hexamethonium	0%
Give TWO agents likely to cause constipation	hexamethonium; morphine	0%
Suppose a patient ingests a drug that partially blocks the delayed rectifier-type K+ channel in the heart. What would happen, if anything, to the Q-T interval?	increase	0%
Look at the next ECG (Trace B). How does it differ from the normal ECG in Trace A?	Less frequent QRS complex	0%
Select one drug that can block voltage-gated Na+ channels	lidocaine	0%
The upstroke of the action potential in cardiac pacemaker cells is due to	L-type voltage gated Ca2+ channels	0%
Bradycardia is produced by acetylcholine action on	M2 muscarinic cardiac receptor	0%
If the elimination rate is expressed in mg/min and plasma concentration in mg/ml, the units of clearance are	ml/min	0%
morphine	mu-receptor agonist	0%
atropine	muscarinic acetylcholine receptor	0%
estrogen	ovaries	0%
The sequence of nerve block by local anaesthetics is	pain first, then general sensory, then motor last	0%
glucagon	pancreas	0%
Give 2 actions which result in histamine secretion	parasympathetic stimulation; stretch	0%
Nicotinic receptors are found in	parasympathetic ganglia	0%
Emptying of the gut is stimulated by	parasympathetic nerves	0%
Histamine is secreted by	parietal cells	0%
Myelination increases conduction velocity because it	permits saltatory conduction	0%
Glucagon is a	polypeptide	0%
For dissolved oxygen, Henry's law states that the amount dissolved is	proportional to concentration	0%
A competitive antagonist of beta1-adrenoceptors	propranolol	0%
Insulin is a	protein	0%
Clearance is defined as the	rate of elimination of drug / plasma concentration	0%
steroids	receptors that modify DNA transcription	0%
A depolarising blocker at the skeletal neuromuscular junction	suxamethonium	0%
calcitonin	thyroid	0%
Troponin C binds calcium and initiates cross bridge cycling.	true	0%
Endothelial cells lining blood vessels can generate nitric oxide	true	0%
NA, by action at beta1-adrenoceptors, increases cAMP levels in the heart.	true	0%
Skeletal muscle fibres have a well-defined t-tubule system.	true	0%
Parasympathetic nerves contract bladder smooth muscle	true	0%
Pulmonary surfactant is produced by	type II alveolar cells	0%
insulin	tyrosine kinase receptors	0%
What does the T wave represent?	ventricular repolarisation	0%
One endocrine function of the kidney is	vitamin D activation	0%
Hyperpolarisation is due to	voltage-gated K+ channel	0%