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Toxicology
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th121
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Last updated: May 24, 2017
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First submitted
May 24, 2017
Times taken
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Average score
2.5%
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Hint
Answer
Opiate overdose symptoms
Respiratory depression
Symptoms
Pinpoint pupils
Symptoms
Unconsciousness
Treatment
Naloxone
Paracetamol mechanism
Glutathione pathway
Symptoms of overdose
None initially
Symptoms
Nausea/vomiting
Symptoms
Abdominal pain
Symptoms
Jaundice
Symptoms
Impaired clotting (INR+++)
Management (<4 hours)
Activated charcoal
Management (>4 hours)
N-acetylcysteine
Stop management when
INR falls below 1.4
Amitriptyline
Treats neuralgia
Symptoms of overdose
Dry mouth
Symptoms
Seizures
Symptoms
Hypotension
Symptoms
Confusion
Symptoms
Arrhythmias
Symptoms
Tachypnoea
Hint
Answer
Symptoms
Tachycardia
Management
Sodium bicarbonate, benzodiazepine, fluids
Organophosphate
Inhibits acetylcholinesterase
Symptoms of poisoning
Muscle cramps
Symptoms
Paralysis
Symptoms
Coma
Parasympathetic overstimulation results in
SLUDGE (saliva, lacrimation, urination, defecation, GI motility, emesis)
Treatment
Atropine
Lithium
Treat bipolar
Overdose mechanism
Electrolyte imbalance
More than 25g means
Severe GI and neurotoxicity
Treatment
Haemodialysis if creatinine and urea are raised
Treatment for mild toxicity
IV fluids
Wernicke's encephalopathy cause
Vitamin B1 deficiency
Cause
Alcoholism
Symptoms
Confusion
Symptoms
Opthalmoplegia
Symptoms
Ataxia
Treatment
Thiamine
Treatment
Glucose
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