Endo - HPA Axis

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Last updated: December 16, 2023

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First submitted	October 30, 2023
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Hint	Reproduction	Metabolism	Lactation	Growth	Stress	Water Balance	Parturition, Lactation
Regulation	Estrogen, progesterone, androgen, prolactin, inhibin	T3	Estrogen, stress	IGF-1	Cortisol, circadian rhythm, stress	Osmolality, intravascular volume	none
Hypothalamus	GnRH	TRH	Dopamine	GHRH, somatostatin	CRH	ADH	Oxytocin
Pituitary	LH, FSH	TSH	Prolactin	GH	ACTH	none	none
Target Gland	Gonads	Thyroid	Breast	Liver	Adrenal cortex	Distal nephron	Uterus, breast
Target Hormones	Estrogen, progesterone, androgen	T3, T4	none	IGF-1, IGF-BP3	Cortisol, androgen	none	none

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