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Statistics for gastrointestinal drugs
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General Stats
- This quiz has been taken 24 times
- The average score is 8 of 21
Answer Stats
| Hint | Answer | % Correct |
|---|---|---|
| what causes it? (GERD top box, ulcers bottom box) | if there is too much pressure on the stomach or the sphincter muscle is dysfunctional | 69%
|
| proton pump inhibitors | 69%
| |
| what is the pathophysiology of peptic ulcers? | an ulcer in an area where the mucosa is saturated in HCl and pepsin of the gastric juices | 62%
|
| what are the drug types used to treat GERD & peptic ulcers? | antacids | 54%
|
| what causes it? (GERD top box, ulcers bottom box) | bacteria (H.pylori) or overuse of NSAIDs | 54%
|
| omeprazole, lansoprazole, etc | 54%
| |
| binds to E1 G-protein coupled receptors on parietal cells, inhibiting adenyl cyclase and decreasing cAMP, blocking acid production | 46%
| |
| H2 receptor antagonists | 46%
| |
| what is the pathophysiology of gastroesophageal reflux disease (GERD)? | occurs when contents of stomach and duodenum backflow into oesophagus, causing inflammation of the oesophageal mucosa (oesophagitis) | 46%
|
| cimetidine, ranitidine, etc | 38%
| |
| M1 muscarinic receptor antagonism, blocking acetylcholine | 38%
| |
| misoprostol | 38%
| |
| competitively blocks H2 histamine receptors, which stimulate gastric acid secretion from parietal cells, to reduce stomach acidity | 31%
| |
| M1 muscarinic receptor antagonists | 31%
| |
| mucosal strengtheners | 31%
| |
| polymerise in the acid environment of the stomach, then binds to the damaged tissue and forms a protective coating over the ulcer beds | 31%
| |
| irreversibly inhibits the hydrogen-potassium ATPase proton pump that controls H+ secretion from parietal cells, reducing gastric acid production | 23%
| |
| pirenzepine, hyoscyamine, etc | 23%
| |
| sucralfate, bismuth chelate, etc | 23%
| |
| prostaglandins | 15%
| |
| what is the mechanism of action of each? | neutralises stomach acid, thereby increasing pH of stomach and allowing mucous layer time to repair itself | 8%
|
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