Statistics for pharmacology - multi choice practice exam

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This quiz has been taken 52 times
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Question	Answer	% Correct
Donepezil is an enzyme inhibitor used in the treatment of Alzheimer’s disease. Which enzyme does it act on?	Acetylcholinesterase	85%
Levodopa, a metabolic precursor of dopamine is used as a primary treatment for Parkinsonism. Which levodopa metabolism inhibitor drug is it normally combined with?	Carbidopa	79%
Which of the following neurotransmitters does not contribute to mood elevation when levels are raised in neuronal synapses?	Acetylcholine	74%
On which cell type in the stomach does pantoprazole act?	Parietal cells	72%
Zolpidem (Stilnox) binds to the omega-1 modulatory site found on which receptor?	The GABA-A receptor	69%
How does galantamine exert its anti-Alzheimers actions?	It enhances the levels of synaptic acetylcholine by inhibiting the acetylcholinesterase enzyme.	62%
Which of the following bronchodilators belongs to the anticholinergic class of drugs?	Ipratropium	59%
Decrease in the levels of vasopressin (ADH) results in	Diabetes Insipidus	56%
Which of the following is NOT an effect of insulin on lipids and fat fuel homeostasis?	Increases lipolysis	54%
Which of the following is used to reverse an opioid overdose?	Naloxone	54%
Which of the following monoclonal antibodies is an anti-inflammatory agent used in the treatment of asthma ?	Omalizumab	54%
Which of the following drugs can be used to help prevent convulsions in pregnancy?	Magnesium sulphate	51%
How does the anti-asthma drug cromolyn exert its anti-inflammatory action?	It is a mast-cell stabiliser preventing the release of inflammatory mediators such as histamine	49%
Which of the following is the definition of pharmacological tolerance?	The decrease in pharmacological effect upon repeated administration of a drug	49%
Overproduction of growth hormone in an adult leads to?	Acromegaly	46%
Which of the following statements is TRUE concerning the posterior pituitary gland?	Anti-diuretic hormone is synthesised in the hypothalamus and transported to the posterior pituitary where it is stored	46%
Which of the following is not a common gastrointestinal tract adverse effect associated with NSAIDs such as aspirin?	Constipation	44%
Which of the following opioids is not present in the opium poppy?	Heroin	44%
How does aspirin exert it’s antiplatelet action?	It is a COX inhibitor	44%
Which of the following is TRUE about the anti-influenza drug zanamivir (Relenza)?	It is a neuraminidase inhibitor	44%
Which of the following antibiotic groups does NOT belong to beta lactam class?	Tetracyclines	44%
Which enzyme is the molecular target for the anticoagulant, warfarin?	Vitamin K oxide reductase	44%
Phenylephrine, a nasal decongestant used in the treatment of allergic rhinitis (hayfever), exerts its effects by acting as:	A selective alpha 1 adrenergic receptor agonist	41%
Which of the following statements regarding the benzodiazepine class of drugs is UNTRUE?	At high doses BZPs relax the spasticity of skeletal muscle by increasing presynaptic inhibition in the spinal cord via GABAB receptors.	41%
CB1 cannabinoid receptors belong to which class of membrane receptors?	Gi-linked G protein-coupled receptors	41%
Osmotic diarrhoea is an adverse effect associated with which of the following antacids?	Magnesium hydroxide	41%
Which of the following statements is true with regards to the opioid class of drugs?	Opioids decrease the motility and increases the tone of intestinal smooth muscle stopping diarrhoea	38%
Which of the following antidepressant drugs exerts its effects by acting as a monoamine oxidase inhibitor (MAOI)?	Phenelzine	38%
Which of the following is NOT classified as a naked monoclonal antibody for use in cancer therapy?	Gemtuzumab ozogamicin	36%
Probenecid is used as a treatment for gout. Probenecid exerts its effects by:	Increases uric acid excretion	36%
How does novocaine exert it’s effects as a local anaesthetic ?	It blocks neuronal sodium ion channels	36%
Which drug class does the anti-cancer drug, bleomycin belong to?	Antibiotic	33%
Anandamide belongs to which class of cannabinoid molecules?	Endocannabinoids	33%
Which of the following human insulin and insulin analogues has the most rapid onset of action	Lispro insulin	33%
Which of the following is a member of the thiazolidinedione class of insulin sensitisers used in the treatment of type II diabetes?	Pioglitazone	33%
Which of the following statements is FALSE with respect to the H5N1 avian influenza virus?	There is difficulty of transmission between birds halting potential global spread	33%
Propylthiouricil is indicated for Graves’ disease. How does it exert its therapeutic effect?	It inhibits synthesis of thyroid hormone by inhibiting the iodination process	31%
Paclitaxel is a drug used to treat non-small cell lung cancer. What is its mechanism of action?	It stabilises microtubules by preventing depolymerisation resulting in the inhibition of the normal dynamic reorganisation of the microtubule network essential for cellular functions	28%
The Oxford-Astra Zeneca vaccine, currently being used in Australia to combat COVID- 19 infections, belongs to which vaccine type?	Viral vector vaccine	28%
Successful molecular therapy has been achieved with a number of genetic diseases. The gene for which enzyme has been successfully introduced into bone marrow as a treatment for patients with severe combined immunodeficiency (bubble boy disease)	Adenosine deaminase	21%