Statistics for P+P Part A's 5

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Answer Stats

Question	Answer	% Correct
Ca2+ through a Ca2+-selective channel	+100mV	100%
An action potential in a myelinated fibre is conducted at 50 m/s and lasts 2 ms. Calculate the distance one action potential occupies.	10cm	100%
What is the typical concentration of intracellular K+?	140mM	100%
What is the typical concentration of intracellular Na+?	15mM	100%
K+ through a non-selective cation channel that is equally permeable to Na+ and K+ but which excludes Ca2+	-15mV	100%
The extracellular calcium concentration	2mM	100%
What is the stoichiometry and direction of Na+ and K+ movements powered by the Na+/K+ATPase in a resting cell?	3Na+ out and 2K+ in	100%
Na+ through a Na+-selective channel	+60mV	100%
K+ through a K+ selective channel	-90mV	100%
What is hormone stimulates sodium reabsorption?	aldosterone	100%
noradrenaline	alpha-adrenoceptors	100%
What drug can block the epithelial sodium channels?	amiloride	100%
Beta-2 adrenoceptor agonist	asthma	100%
isoprenaline	beta-2-adrenoceptor	100%
A calcium binding protein that mediates the effects of calcium	calmodulin	100%
What is the main force driving fluid out of capillaries?	capillary hydrostatic pressure	100%
atropine	cardiac acetylcholine receptor	100%
Na+ channel blocker	cardiac dysrhythmia	100%
What hormone inhibits acid generation?	cholecystokinin	100%
What type of capillary is found in skeletal muscle?	continuous	100%
Myelination increases conduction velocity because it	decreases membrane capacitance	100%
Where does the rest of sodium reabsorption occur?	distal collecting tubules	100%
Sodium ions leave the lumen to enter cells by crossing the apical membrane. How does this transport occur?	epithelial sodium channels (ENaC)	100%
What type of capillary is found in the kidney?	fenestrated	100%
trimetaphan	ganglion blocker	100%
nicotine	ganglionic acetylcholine receptors	100%
What hormone stimulates acid production?	gastrin	100%
What does omeprazole target?	H+/K+ATPase	100%
Inhibitor of angiotensin converting enzyme	hypertension	100%
Select one factor that can increase conduction velocity	increase membrane resistance	100%
One mechanism that releases the ion from the endoplasmic (or sarcoplasmic) reticulum	IP3	100%
What would happen to the reversal potential for K+ if the extracellular K+ concentration increased?	it would become more depolarised	100%
Select a drug that can suppress the generation of a neuronal action potential by blocking voltage-gated Na+ channels	lignocaine	100%
A clinical use of a voltage-gated Na+ channel blocker is	local anaesthetic	100%
At rest, is the normal cell membrane more permeable to Na+ or K+?	more permeable to K+	100%
Cholinesterase inhibitors	myasthenia gravis	100%
A calcium-activated enzyme that stimulates smooth muscle contraction	myosin light chain kinase	100%
What drug blocks acid secretion?	omeprazole	100%
A drug that will block the Na+/K+ ATPase.	ouabain	100%
Cyclooxygenase inhibitor	pain killer	100%
What cells in the stomach secrete gastric acid?	parietal cells	100%
What is the main force driving fluid reabsorption?	plasma colloid osmotic pressure	100%
Where does the bulk of sodium reabsorption occur?	proximal tubule	100%
What type of capillary is found in the liver	sinusoidal	100%
An inhibitor of a voltage-operated Ca2+ channel	verapamil	100%