Bacteria 5 (toxins)

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Quiz by MedSoc
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Last updated: April 3, 2019
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First submittedApril 3, 2019
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Hint
Answer
Pertussis toxin and which other ADP-ribosylate regulators of adenylate cyclase, leading to disturbance of CAMP levels,signalling and ion balance?
Cholera
Which toxin targets translation elongation factor 2, leading to arrest of protein synthesis?
Diptheria
What toxin is a glycosidase that depurinates 28S rRNA, blocking protein synthesis?
Shiga
What antibiotic resistant bacteria's toxin glucosylate small GTPases involved in signal transduction, disrupting actin cytoskeleton?
Clostridium difficile
What deamidase that targets host cell GTPases, disrupting cell signal transduction is produced by UPEC?
Cytotoxic Necrotizing Factor
What type of toxin are both tetanus and botulinum toxin?
Neurotoxin
Hint
Answer
What does the A-chain of tetanus cleave leading to the prevention of release of inhibitory neurotransmitter?
Synaptobrevin
What type of paralysis does botulinum toxin lead to?
Flaccid
What is the end result of over stimulation of T cells due to super antigens?
Cytokine storm
What bacteria producing superantigens leads to toxic shock syndrome?
Staph. aureus
What component of LPS also known as endotoxin triggers acute inflammation?
Lipid A
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