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APP Part A's: General Anaesthetic

Want to take this awesome quiz on general anaesthetics? Go ahead, knock yourself out!
Quiz by genes644
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Last updated: August 6, 2022
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First submittedAugust 6, 2022
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Average score4.2%
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Question
Answer
Name a currently used inhaled anaesthetic?
Nitrous oxide
Isoflurane
Desflurane
Sevoflurane (used in maintenance of GA, extremely fast onset and offset)
Halothane
Name an injected anaesthetic?
Thiopental
Ketamine
Propofol
Diazepam
Nitrous oxide (administration)
Inhaled agent
very weak anaesthetic
MAC greater than 100%
extremely high plasma solubility
Propofol
IV
Barbiturate
hypnotic
most commonly used agent
short acting
Name 2 possible targets of general anaesthetics
Lipid membrane
Name 2 possible targets of general anaesthetics
Proteins
Diclofenac
NSAID used in GA
What happens in stage 4 anaesthesia?
Overdose
Question
Answer
What happens in stage 3 anaesthesia?
“surgical anaesthesia” muscles relax
What drug is most commonly used in the UK?
Propofol
What can reverse neuromuscular blocking?
Acetylcholinesterase inhibitors e.g. neostigmine, physostigmine
Side effects of acetylcholinesterase inhibitors include:
Pro-muscarinic effects
bradycardia
hypotension
hypersecretion
bronchoconstriction
GI tract hypermobility
decreased intraocular pressure
What are acetylcholinesterase inhibitors used for?
Myasthenia gravis, Alzheimer’s, Glaucoma,
Vasoconstrictors are used in order to control systemic what?
Vasodilation (helps prevent hypotension and hypothermia induced by excessive cooling)
minimise bleeding
The mechanism of action of the vasoconstrictors
A1 activation
Parasympatholytics (muscarinic antagonist) are applied in order to control what?
Reduces PSNS activity
Reduces salivation
Reduces respiratory tract secretion e.g. glycopyrrolate
Question
Answer
Active warming is used to manage what?
The loss of thermoregulatory control through peripheral vasodilation (causes cooling)
What is used to reverse the effects of a neuromuscular blocker and what is used to prevent the effects of this reverser?
Acetylcholinesterase e.g. neostigmine and physostigmine. Muscarinic antagonist
Short acting local anaesthetics are used during GA to (+ examples)
Reduce post-operative pain.
Lidocaine
bupivacaine
Codeine
Centrally acting opiate used for analgesic effect
Morphine
Opiate analgesic used as adjuvant in general anaesthesia.
Produces respiratory depression and hypothermia.
U opioid receptor agonist
Ondansetron
Antiemetic
blocks 5HT3 receptor
Centrally (deactivates vomiting centre in medulla oblongata)
peripherally (blocks receptors in chemoreceptor trigger zone)
Temazepam
Anxiolytic
Diclofenac
NSAID used in GA
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