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Statistics for Drug-receptor interactions

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General Stats

This quiz has been taken 2 times
The average score is 2 of 16

Answer Stats

Hint	Answer	% Correct
What type of molecule when it binds to a receptor produces (increases) a response?	Agonist	100%
What about a ligand determines how much of it binds to a receptor given its concentration?	Affinity	50%
Addition of a competetive antagonist will shift a log concentration/response curve in what direction?	Right	50%
This phenomenon has 2 key forms for Beta adrenoreceptors, heterologous and homologous. In heterologous PKA phosophorylates the receptor but is not specific, in homologous, what enzyme phosphorylates it?	Beta-adrenoreceptor kinase/BARK	0%
After this the binding of what protein uncouples the receptor?	Beta arrestin	0%
What is it called when a receptor requires more than one molecule binding to be activated?	Co-operativity	0%
What phenomenon is seen when after a prolonged exposure to an agonist the receptor is prevented from producing its normal effect?	Desensitization	0%
What type of molecules are used to switch the channels between modes (0=channel not open, 1=channel opening in bursts, 2=very long openings)?	Dihydropyridines/DHP	0%
Three processes are involved in this phenomenon uncoupling, sequestration and last?	Down-regulation	0%
What is the relationship between the amount of receptors occupied and the size of the response?	Efficacy	0%
Which type of this phenomenon occurs with high concentrations of ligand?	Homologous	0%
In alphabetical order what are the three types of voltage gated Ca2+ channels found in muscle?	L, N and T	0%
What molecule does cAMP produced by adenyly cyclase control cell functions through?	Protein Kinase A/PKA	0%
A sequence of experiments to determine the relative potency of a group of structurally related compounds is a what?	Structure activity series	0%
What type of receptor sometimes requires dimerization in order to autophosphorylate?	Tyrosine kinase	0%
What is it called if a drug is more effective when the target is being used more frequently?	Use dependence	0%

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