Intro to the Neuron (1)

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Quiz by MedSoc
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Last updated: December 11, 2018
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First submittedDecember 11, 2018
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Hint
Answer
To the nearest 10 roughly what is the average external Na ion concentration in human neurons? (mM)
150
To the nearest 5 roughly what is the average internal Na ion concentration in human neurons? (mM)
15
What is the name of the equation that can be used to determine equilibrium potential when the membrane is permeable to one ion only?
Nernst
Chloride ions are normally extruded by secondary active processes, when couped to movement of K ions what is the name of the transporter?
KCC2
When coupled to the sodium-dependant flux of HCO3- ions, what is the transporter?
NDCBE
In an action potential what is the name given to the point where inward current carried by Na+ ions just exceeds outward current across the resting membrane?
Threshold
What is the most common type of electrical synapse?
Gap junction
Fusion of neurotransmitters with presynaptic membranes for exocytosis is controlled by v (vesicle) and t (target) proteins but what is the name of them?
SNARE
Hint
Answer
On the vesicle what is the Ca2+ion sensor called?
Synaptotagmin
What is the name for the protein on the vesicle that binds to the SNAP-25 and syntaxin on the plasma membrane?
Synaptobrevin
What is the name for a receptor which triggers a secondary messenger cascade when stimulated?
Metabotropic
What type of receptor has a quicker transmission?
Ionotropic
What is the primary excitatory transmitter in the CNS?
Glutamate
GABA is one but what is the other major inhibitory transmitter in the CNS?
Glycine
What is now considered a gasous neurotransmitter which was known as endothelium-derived relaxing factor?
NO
NMDA and AMPA are both ionotropic glutamatergic channels, but which sometimes allows the entrance of divalent cations (e.g. Ca2+)?
NMDA
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