Hint | Answer | % Correct | |
---|---|---|---|
Loop Diuretic | Blocks NKCC in TAL Hypokalaemia Venodilation Uric Acid Retention Ca + Mg Excretion | Furosemide | 80%
|
Potassium Sparring Diuretic | Inhibits Aldosterone via carenone salt AldR competition | Spironolactone | 80%
|
ACE inhibitor | ↑Bradykinin (inflam+pain) so use AIIR inhib instead | Ramipril | 60%
|
Calcium Channel Blocker | Phenylalkylamine | Verapamil | 60%
|
Calcium Channel Blocker | Dihydropyridine | Amlodipine | 40%
|
Factor Xa Inhibitor | Apixaban | 40%
| |
Class II Dysrhythmic | beta1 adrenoceptor antagonist | Atenolol | 40%
|
Thiazide Diuretic | Blocks Na-Cl Cotransport in DCT Hypokalaemia Uric Acid retention Ca + Mg Excretion Increases blood glucose | Bendroflumethiazide | 40%
|
SGLT Inhibitor | Lowers blood glucose as well | Dapagliflozin | 40%
|
NCX Inhibitor | Cardiac Glycoside | Digoxin | 40%
|
Calcium Channel Blocker | Benzothiazepine | Diltiazem | 40%
|
Class Ic Dysrhythmic | Slow, no AP effects | Flecainide | 40%
|
Osmotic Diuretic | Treat Cerebral Oedema (no BBB crossing) | Mannitol | 40%
|
Gp IIb/IIIa inhibitor | Abciximab | 20%
| |
Carbonic Anhydrase Inhibitor | vs Glaucoma + altitude sickness | Acetazolamide | 20%
|
Renin Inhibitor | Aliskiren | 20%
| |
Activates Plasminogen | TIssue plasminogen activator made from recombinant DNA | Altepase | 20%
|
Class III Dysrhythmic | Inhibits inwards Na + outwards K prolongs AP and refractory period | Amiodarone | 20%
|
Slow release anti-clot | Plasminogen + anisoylated streptokinase | Anistreplase | 20%
|
Thrombin Inhibitor | Reduce HIT | Argatroban | 20%
|
VGNaC Toxin | Prevents inactivation of NaC | Batrachotoxin | 20%
|
Local Anaesthetic | pKA 2.6 (99% unprotonated at normal pH) | Benzocaine | 20%
|
Thrombin Inhibitor | Leech Saliva homologue | Bivalirudin | 20%
|
ADP-Platelet Receptor Inhibitor | Ineffective vs homozygous CYP2C19 mutations | Clopidogrel | 20%
|
Thrombin Inhibitor | Treat A-Fib, use prophylactically for surgery | Dabigatran | 20%
|
Low Weight Heparin | Reduce HIT | Danaparoid | 20%
|
b1 AR Agonist | Increase CO but increases O2 demand Use antagonist to reduce adrenergic toxicity | Dobutamine | 20%
|
Thrombin Inhibitor | Activates antiThrombin III Causes thrombocytopenia | Heparin | 20%
|
Calcium Sensitiser | Increases binding to Troponin. Inhibits PDE | Levosimendan | 20%
|
Local Anaesthetic | Use dependence | Lidocaine | 20%
|
Class Ib Dysrhythmic | Fast, shortens AP | Lidocaine | 20%
|
AT1R Inhibitor | Prevents Angiotensin 2 action | Losartan | 20%
|
NCX Inhibitor | Cardiac Glycoside | Ouabain | 20%
|
Class Ia Dysrhythmic | Medium duration, lengthens AP | Quinidine | 20%
|
Activates Plasminogen Activator | From Streptomycin | Streptokinase | 20%
|
K-ATP antagonist | ATP Analogue | Sulphonylurea | 20%
|
Local Anaesthetic | pKA 8.5 (less effective at lower pH) | Tetracaine | 20%
|
VGNaC Toxin | Binds Glu on S6 Domain IV | Tetrodotoxin | 20%
|
Gp IIb/IIIa Inhibitor | Prevents Fibrin and vWF binding | Tirofiban | 20%
|
Plasminogen Inhibitor | Tranexamic Acid | 20%
| |
Class IV Dysrythmic | L-Type calcium channel blocker | Verapamil | 20%
|
Thrombin Inhibitor | Prevents synth of Factors 2,7,9,10 Interacts with food a lot | Warfarin | 20%
|
Potassium Sparring Diuretic | Inhibits ENaC in DCT | Amiloride | 0%
|
Non-Diuretic Thiazide | Opens K-ATP for more Insulin Vasodilator | Diazoxide | 0%
|
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