parasympathetic & sympathetic drugs

adrenergic agonists & antagonists, parasympathomimetics & parasympatholytics, cholinesterase inhibitors & NM blockers

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Last updated: April 18, 2023

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First submitted	April 18, 2023
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What are the adrenergic agonists?	What receptors do they work on?	What kind of agonist are they?	What are the common uses?
Adrenaline	alpha 1, alpha 2, beta 1, beta 2	mixed agonist	anaphylaxis	constant rate infusions for dangerous hypotension	added to other drugs to improve their efficacy	cardiac arrest
Noradrenaline	alpha 1, alpha 2, beta 1	mixed agonist	anaphylaxis	constant rate infusions for dangerous hypotension	added to other drugs to improve their efficacy	cardiac arrest
Dopamine	alpha 1, alpha 2, beta 1	mixed agonist	vasodilation (low doses)	myocardial contraction (medium doses)	vasoconstriction (high doses)
Pseudoephedrine	alpha 1, alpha 2, beta 1, beta 2	alpha agonist	nasal decongestant
Phenylephrine	alpha 1, alpha 2	alpha agonist	nasal decongestant		ocular decongestant
Salbutamol	beta 2	beta 2 agonist	asthma		chronic obstructive pulmonary disease (COPD)

What are the adrenergic antagonists?	What receptors do they work on?	What are the common uses?
Prazosin	alpha 1	cardiovascular reasons (vasodilation)
Propranolol	beta 1, beta 2	cardiovascular reasons (antiarrhythmic and vasodilation)
Atenolol	beta 1	cardiovascular reasons (antiarrhythmic and vasodilation)

What is the parasympathomimetic?	What kind of agonist/antagonist is it?	What is it used for?	What are the parasympatholytics?	What kind of agonist/antagonists are they?	What are the common uses?
Bethanecol	muscarinic agonist	atonic (stretched) bladder	Atropine	competitive antagonists (antimuscarinics)	cardiovascular reasons
			Tropicamide		ophthalmic use (ciliary muscle paralysis to relieve ciliary spasm)
			Ipratropium		respiratory use (green inhalers for bronchodilation)
			Scopolamine		gastrointestinal use (decrease abdominal pain associated with GIT cramping)

What are the cholinesterase inhibitors?	What are they used for?		What is the neuromuscular blocker?	What type of agonist/antagonist is it?	What are the common uses for it?
Neostigmine	diagnosis of Myasthenia gravis	antidotes to NM blockers	Atracurium	competitive nicotinic antagonist	paralysis of extraocular skeletal muscles during intraocular surgery (eg. cataract surgery)
Pyridostigmine
Edrophonium					paralysis of respiratory skeletal muscles during a thoracotomy